ArticleInternal medicine (Tokyo, Japan)2026
Bloodstream Infection Caused by Mycobacterium neoaurum in a Primary Central Nervous System Lymphoma Patient with Toxic Epidermal Necrolysis.
Article in Internal medicine (Tokyo, Japan), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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15 authors.
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Abstract
Mycobacterium neoaurum is a rare cause of bacteremia, predominantly affecting immunocompromised hosts with indwelling catheters. A 75-year-old man receiving high-dose methotrexate therapy for primary central nervous system lymphoma without a central venous catheter (CVC) presented with fever. The acid-fast bacilli isolated from his blood cultures were identified as M. neoaurum through 16S rRNA sequencing. Despite broad-spectrum antimicrobial therapy, the patient developed persistent pancytopenia and toxic epidermal necrolysis, which ultimately led to multiple organ failure. M. neoaurum should be considered a potential pathogen in immunocompromised hosts, even in the absence of a CVC. Rapid identification and appropriate antimicrobial selection are essential when mycobacteria are isolated from blood culture.
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