Evidence map›Paper›PMID 40866045›Full record

ArticleJACC. Basic to translational science2025

Cigarette Tar Enhanced ECs Pyroptosis via CAMKII/Drp1/mtDNA: Novel Insight Into the Mechanism of Plaque Erosion.

Xing Luo, Ji Li, Yuwu Chen, Xiuzhu Weng, Xiaoyi Bao, Xiaoxuan Bai, Ying Lv, Shan Zhang, Xinxin Zhu, Biyi Xu and 12 more

Abstract read
In one paragraph

Article in JACC. Basic to translational science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. CIITA/PRMT5 promote CD4BMC medicine · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Xing LuoDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Ji LiDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Yuwu ChenDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Xiuzhu WengDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Xiaoyi BaoDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Xiaoxuan BaiDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Ying LvDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Shan ZhangDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Xinxin ZhuDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Biyi XuDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Chen ZhaoDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Ming ZengDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Tianyu WuDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Qianhui SunDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Shengfang WangDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Minghao LiuDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Thomas JohnsonDepartment of Cardiology, Bristol Heart Institute, Bristol, United Kingdom.
Stephen J WhiteFaculty of Medical Sciences, The Medical School, Newcastle University, Newcastle Upon Tyne, United Kingdom.
Peter LibbyDivision of Cardiovascular Medicine, Brigham and Women's Hospital, Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts, USA.
Sining HuDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China.
Bo YuDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China. Electronic address: yubodr@163.com.
Haibo JiaDepartment of Cardiology of the Second Affiliated Hospital, Harbin Medical University, State Key Laboratory of Frigid Zone Cardiovascular Diseases (SKLFZCD), Nangang District, Harbin, China; Key Laboratory of Myocardial Ischemia, Ministry of Education, Nangang District, Harbin, China. Electronic address: jhb101180@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smoking is the only cardiovascular risk factor for plaque erosion. We found cigarette tar resulted in erosion-like lesion development in apolipoprotein E

Indexed as

cigarette tarendothelial cellsplaque erosionpyroptosis

Identifiers

PMID40866045
PMCPMC12399138

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.