Evidence map›Paper›PMID 40865875›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2025

Tolerogenic lung allograft microenvironment suppresses pathogenic tissue remodeling following respiratory virus infection in mice.

Ítalo de Araújo Castro, Yuriko Terada, Yuhei Yokoyama, Amit I Bery, Wenjun Li, Junedh M Amrute, Charles R Liu, Yun Zhu Bai, Victoria Gnazzo, Hēth R Turnquist and 8 more

Abstract read
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ítalo de Araújo CastroDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA; Center for Women's Infectious Diseases Research, Washington University in St. Louis, St. Louis, Missouri, USA.
Yuriko TeradaDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Yuhei YokoyamaDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Amit I BeryDepartment of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA.
Wenjun LiDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Junedh M AmruteDepartment of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA.
Charles R LiuDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Yun Zhu BaiDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri, USA.
Victoria GnazzoDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA; Center for Women's Infectious Diseases Research, Washington University in St. Louis, St. Louis, Missouri, USA.
Hēth R TurnquistDepartment of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Kory J LavineDepartment of Medicine, Washington University in St. Louis, St. Louis, Missouri, USA.
Alexander S KrupnickDepartment of Surgery, University of Maryland, Baltimore, Maryland, USA.
Andrew E GelmanDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri, USA; Department of Pathology & Immunology, Washington University in St. Louis, St. Louis, Missouri, USA.
Jon H RitterDepartment of Pathology & Immunology, Washington University in St. Louis, St. Louis, Missouri, USA.
Joshua A BlatterDepartment of Pediatrics, Washington University in St. Louis, St. Louis, Missouri, USA.
David WangDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA; Department of Pathology & Immunology, Washington University in St. Louis, St. Louis, Missouri, USA.
Carolina B LópezDepartment of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, USA; Center for Women's Infectious Diseases Research, Washington University in St. Louis, St. Louis, Missouri, USA. Electronic address: clopezzalaquett@wustl.edu.
Daniel KreiselDepartment of Surgery, Washington University in St. Louis, St. Louis, Missouri, USA; Department of Pathology & Immunology, Washington University in St. Louis, St. Louis, Missouri, USA. Electronic address: kreiseld@wustl.edu.

Funding

The Role of Neutrophils in Regulating Lung Transplant ToleranceP01AI116501 · NIAID · WASHINGTON UNIVERSITY · PI ALEXANDER S. KRUPNICK · 2015 to 2026
$19.4M
PRINCIPLES IN PULMONARY RESEARCHT32HL007317 · NHLBI · WASHINGTON UNIVERSITY · PI Steven Brody, Michael J Holtzman · 1985 to 2026
$16.1M
THE ROLE OF ISCHEMIA REPERFUSION INJURY IN LUNG ALLOGRAFT REJECTIONR01HL094601 · NHLBI · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman, Daniel Kreisel · 2009 to 2026
$6.9M
Immunoregulatory Mechanisms of IL-33 in Heart TransplantationR01HL122489 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Heth R Turnquist · 2015 to 2026
$4.9M
Specification and Function of Tissue Resident and Recruited Macrophages in Cardiac Remodeling and Heart FailureR35HL161185 · NHLBI · WASHINGTON UNIVERSITY · PI Kory J. Lavine · 2022 to 2026
$4.3M
Defective Viral genomes in RSV pathogenesisR01AI137062 · NIAID · WASHINGTON UNIVERSITY · PI Carolina B. Lopez · 2018 to 2026
$4.2M
The Role of Eosinophils in the Lung AllograftR01AI145108 · NIAID · UNIVERSITY OF VIRGINIA · PI Elizabeth A Jacobsen, ALEXANDER S. KRUPNICK · 2019 to 2026
$4.1M
The Role of Donor Innate Immune Responses in Regulating Alloimmunity after Heart TransplantationR01HL151078 · NHLBI · WASHINGTON UNIVERSITY · PI KREISEL, DANIEL, LAVINE, KORY J. · 2020 to 2023
$2.6M
Targeting a Defined Surgical Stress-Induced Inflammatory Pathway to Improve Peri-Operative OutcomesR01HL166402 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI Elizabeth A Jacobsen, ALEXANDER S. KRUPNICK · 2023 to 2026
$2.2M
THE VIROME AND ADVERSE OUTCOMES IN LUNG TRANSPLANTATIONR33HL137079 · NHLBI · WASHINGTON UNIVERSITY · PI WANG, DAVID · 2019 to 2021
$2.1M
BLRD VA I01 BX002299BLRD VA I01 BX002730NHLBI NIH HHS R01 HL094601NHLBI NIH HHS R01 HL122489NHLBI NIH HHS R01 HL151078NHLBI NIH HHS R01 HL166402NHLBI NIH HHS R33 HL137079NHLBI NIH HHS R35 HL161185NHLBI NIH HHS T32 HL007317NIAID NIH HHS P01 AI116501NIAID NIH HHS R01 AI137062NIAID NIH HHS R01 AI145108
6 · The paper itself

Abstract

Tolerance after lung transplantation is associated with the induction of Foxp3

Indexed as

Graft RejectionImmune ToleranceLung TransplantationRespiratory Tract InfectionsTransplantation ToleranceAllograftsAmphiregulinAnimalsForkhead Transcription FactorsGraft SurvivalMaleMiceMice, Inbred BALB CMice, Inbred C57BLT-Lymphocytes, RegulatoryAmphiregulinForkhead Transcription FactorsAmphiregulinlung transplantationrespiratory viral infectiontissue repair

Identifiers

PMID40865875
PMCPMC12596023

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.