Evidence map›Paper›PMID 40864852›Full record

ArticleAnalytical chemistry2025

MALDI-TIMS-MS

Robert A Shepherd, Gordon T Luu, Laura M Sanchez

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Robert A ShepherdDepartment of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California 95064, United States.
Gordon T LuuBruker Scientific LLC, Billerica, Massachusetts 01821, United States.
Laura M SanchezDepartment of Chemistry and Biochemistry, University of California Santa Cruz, Santa Cruz, California 95064, United States.ORCID 0000-0001-9223-7977

Funding

Development of a high throughput platform for screening directed evolution librariesR21GM148870 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI SANCHEZ, LAURA MARGARET · 2023 to 2024
$430k
NIGMS NIH HHS R21 GM148870
6 · The paper itself

Abstract

Mass spectrometry imaging (MSI) is a powerful tool for monitoring the spatial distributions of microbial metabolites directly from culture. MSI can identify secretion and retention patterns for microbial metabolites, allowing for the assessment of chemical communication within complex microbial communities. Microbial imaging via matrix-assisted laser desorption/ionization (MALDI) MSI remains challenging due to high sample complexity and heterogeneity associated with the required sample preparation, making annotation of molecules by MS

Indexed as

Biological ProductsFungiIon Mobility SpectrometrySpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationCoculture TechniquesBiological Products

Identifiers

PMID40864852
PMCPMC12413305

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.