Evidence map›Paper›PMID 40864826›Full record

ArticleCurrent issues in molecular biology2025

Cloning and Functional Characterization of a Novel Brevinin-1-Type Peptide from

Huyen Thi La, Quynh Bach Thi Nhu, Hai Manh Tran, Huyen Thi Ngo, Phuc Minh Thi Le, Hanh Hong Hoang, Linh Trong Nguyen, Dat Tien Nguyen, Thanh Quang Ta

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Huyen Thi LaInstitute of Biology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
Quynh Bach Thi NhuFaculty of Medical Technology, Hai Phong University of Medicine and Pharmacy, Hai Phong 180000, Vietnam.
Hai Manh TranInstitute of Biology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.ORCID 0009-0006-9079-8547
Huyen Thi NgoInstitute of Biology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.ORCID 0009-0005-9182-1932
Phuc Minh Thi LeInstitute of Biology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
Hanh Hong HoangInstitute of Biology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
Linh Trong NguyenInstitute of Biology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.ORCID 0009-0001-5067-4092
Dat Tien NguyenCenter for High Technology Research and Development, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
Thanh Quang TaBac Thang Long Hospital, Hanoi 100000, Vietnam.

Funding

Vietnam Academy of Science and Technology TĐDIOX.04/22-24
6 · The paper itself

Abstract

Despite significant medical advancements, two major health challenges persist: antibiotic resistance in microbial pathogens and drug resistance in cancer cells. To address these issues, research has increasingly focused on discovering novel natural compounds with dual antimicrobial and anticancer activities. Among such candidates, antimicrobial peptides (AMPs) have attracted attention due to their ability to selectively target microbial and cancer cells while exhibiting minimal toxicity toward normal cells. Although Vietnam possesses rich biodiversity, including a wide range of Anura species, studies on AMPs from these organisms remain limited. In this study, a novel AMP, brevinin-1 E8.13, was identified from the skin secretion of

Indexed as

anticancer activityantimicrobial peptidesbrevinin-1 E8.13CAFLUX HepG2 cellsskin secretionSylvirana guentheri

Identifiers

PMID40864826
PMCPMC12412326

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.