Evidence map›Paper›PMID 40864746›Full record

ArticleCurrent issues in molecular biology2025

A Preliminary Approach to Oral Low-Dose Ketamine Self-Administration in Mice (

Cláudia A Rocha, Luís Sampaio, Luís M Félix, Sandra M Monteiro, Luís Antunes, Carlos Venâncio

Abstract read
In one paragraph

Article in Current issues in molecular biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cláudia A RochaSchool of Life and Environmental Sciences (ECVA), University of Trás-Os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0009-0005-0322-9489
Luís SampaioSchool of Life and Environmental Sciences (ECVA), University of Trás-Os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.
Luís M FélixCentre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-Os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0001-9870-6666
Sandra M MonteiroSchool of Life and Environmental Sciences (ECVA), University of Trás-Os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0002-4026-5965
Luís AntunesCentre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-Os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0002-9757-6879
Carlos VenâncioCentre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), University of Trás-Os-Montes and Alto Douro (UTAD), 5000-801 Vila Real, Portugal.ORCID 0000-0003-3880-3442

Funding

Fundação para a Ciência e Tecnologia 2021.00458.CEECINDFundação para a Ciência e Tecnologia LA/P/0126/2020Fundação para a Ciência e Tecnologia UIDB/04033/2020
6 · The paper itself

Abstract

With ketamine gaining attention as a therapeutic drug, oral administration offers an effective alternative to traditional parenteral routes. However, a significant gap remains in understanding its use via voluntary ingestion. This preliminary study aimed to explore the feasibility of oral ketamine self-administration in mice (

Indexed as

ketaminelow dosesmiceoral administrationoxidative stress

Identifiers

PMID40864746
PMCPMC12384402

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.