ArticleDiscover oncology2025
A 40-year bibliometric analysis of global research on neoadjuvant chemotherapy for oral cancer (1985-2024).
Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeoadjuvant chemotherapy (NAC) has become a critical component in the treatment of oral cancer, enhancing tumor resectability and improving patient survival. This study aimed to perform a bibliometric analysis to systematically explore global research trends, key contributors, and emerging hotspots in NAC for oral cancer.
methodsPublications from 1985 to 2024 were retrieved from the Web of Science Core Collection. Bibliometric data were analyzed using R (version 4.3.3), VOSviewer (version 1.6.20), and CiteSpace (version 6.3.R1). These tools were employed to examine publication trends, co-authorship networks, institutional collaborations, and keyword co-occurrence and burst analysis.
resultsA total of 235 publications were identified, showing an annual growth rate of 7%. Japan led in publication output (47 publications), followed by China (38) and Germany (33), while the United States exhibited the strongest international collaboration. Chang Gung Memorial Hospital was the leading contributor, with 51 publications. The leading journals included Oral Oncology, Head and Neck, and the Journal of Cranio-Maxillofacial Surgery. Kreppel Matthias ranked first with an H-index of 9, 10 publications, and 234 total citations. Emerging research hotspots focused on "induction chemotherapy", "biomarker expression", and "multidisciplinary management".
conclusionThis study provides a bibliometric analysis of global research trends and hotspots in NAC for oral cancer, offering valuable insights into key contributors, emerging themes, and collaborative networks. The findings have significant implications for guiding future research directions and integrating evidence-based strategies into clinical practice to improve patient outcomes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.