Evidence map›Paper›PMID 40864352›Full record

ReviewTopics in current chemistry (Cham)2025

Prospects, Advances, and Applications of BioMOF-Based Platforms.

Fangxia Zhao, Xunnan Wan, Yan Liang, Weidong Liu, Jianqiang Liu, Ying Pan, Alireza Nezamzadeh-Ejhieh, Xiaoxiu Li

Abstract readReview
PubMed Publisher
In one paragraph

Review in Topics in current chemistry (Cham), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fangxia Zhao *The First Clinical Medical College of Guangdong Medical University, Zhanjiang, 524002, Guangdong Province, China.
Xunnan Wan *Dongguan Key Laboratory of Drug Design and Formulation Technology, School of Pharmacy, Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, Guangdong Medical University, Dongguan, 523808, China.
Yan Liang *Dongguan Key Laboratory of Drug Design and Formulation Technology, School of Pharmacy, Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, Guangdong Medical University, Dongguan, 523808, China.
Weidong LiuThe First Clinical Medical College of Guangdong Medical University, Zhanjiang, 524002, Guangdong Province, China. liuweidong10571@163.com.
Jianqiang LiuDongguan Key Laboratory of Drug Design and Formulation Technology, School of Pharmacy, Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, Guangdong Medical University, Dongguan, 523808, China. jianqiangliu2010@126.com.
Ying PanDongguan Key Laboratory of Drug Design and Formulation Technology, School of Pharmacy, Guangdong Medical University Key Laboratory of Research and Development of New Medical Materials, Guangdong Medical University, Dongguan, 523808, China. yingpan@gdmu.edu.cn.
Alireza Nezamzadeh-EjhiehChemistry Department, Shahreza Branch, Islamic Azad University, Shahreza, Isfahan, Iran.
Xiaoxiu LiThe First Clinical Medical College of Guangdong Medical University, Zhanjiang, 524002, Guangdong Province, China. 13316680551@189.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bio-metal-organic frameworks (bio-MOFs) have emerged as a revolutionary group of hybrid materials distinguished by their exceptional biocompatibility, programmable biodegradability, and host-guest molecular recognition capabilities. This review systematically examines recent advancements in bio-MOF engineering, with particular focus on the innovative synthesis strategies and the structure-property relationships arising from their tunable pore architectures and surface functionalities. The mechanistic foundations of bio-MOFs in targeted drug delivery systems, contrast-enhanced bioimaging, and multifunctional therapeutic interventions combining anti-inflammatory and antibacterial actions are discussed in detail. Finally, in terms of future perspectives, we discuss emerging opportunities in other delivery systems, personalized medicine platforms, and sustainable environmental applications, underscoring the necessity for cross-disciplinary collaboration between materials science and molecular biology to unlock the full potential of these biohybrid systems.

Indexed as

Biocompatible MaterialsMetal-Organic FrameworksAnimalsAnti-Bacterial AgentsAnti-Inflammatory AgentsDrug Delivery SystemsHumansAnti-Bacterial AgentsAnti-Inflammatory AgentsBiocompatible MaterialsMetal-Organic FrameworksAdsorptionAntibacterial therapyBioimagingBio-MOFCancer therapyDrug delivery

Identifiers

PMID40864352

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.