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ArticleClinical and experimental nephrology2025

Impact of kidney function and leisure activities on disability risk among community-dwelling older adults.

Takahiro Shimoda, Kouki Tomida, Chika Nakajima, Ayuka Kawakami, Hiroyuki Shimada

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Article in Clinical and experimental nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Takahiro ShimodaDepartment of Preventive Gerontology Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan. tshimoda@ncgg.go.jp.ORCID http://orcid.org/0000-0003-1914-9721
Kouki TomidaDepartment of Preventive Gerontology Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.
Chika NakajimaDepartment of Preventive Gerontology Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.
Ayuka KawakamiDepartment of Preventive Gerontology Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.
Hiroyuki ShimadaDepartment of Preventive Gerontology Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, 7-430 Morioka-Cho, Obu, Aichi, 474-8511, Japan.

Funding

Japan Agency for Medical Research and Development JP15dk0207019Japan Agency for Medical Research and Development JP18dk0110021Japan Agency for Medical Research and Development JP18le0110004Japan Society for the Promotion of Science JP23K19916Japan Society for the Promotion of Science JP26702033Ministry of Health, Labour and Welfare H24-tyoujyu-ippan-004National Center for Geriatrics and Gerontology 21-26National Center for Geriatrics and Gerontology 24-18National Center for Geriatrics and Gerontology 25-26National Center for Geriatrics and Gerontology 26-33National Center for Geriatrics and Gerontology 27-22National Center for Geriatrics and Gerontology 28-30
6 · The paper itself

Abstract

backgroundImpaired kidney function has been shown to be associated with both leisure activity participation and disability incidence. However, whether kidney function could influence the association between leisure activity and disability incidence in older adults remains unclear. Therefore, in the present study, we aimed to examine the influence of kidney function on the association between leisure activities and incident disability among community-dwelling older adults.

methodsWe enrolled 16,354 community-dwelling older adults from the National Center for Geriatrics and Gerontology-Study of Geriatric Syndromes. The estimated glomerular filtration rate (eGFR) was determined based on creatinine levels; the participants were classified into two categories: eGFR ≥ 60 mL/min/1.73 m

resultsOverall, 786 (5.0%) patients developed a disability within 24 (interquartile range 24-24) months. Using Cox proportional hazards regression models adjusted for potential confounders, low leisure activity participation was identified as a significant factor for increased risk of disability (hazard ratio 1.25; 95% confidence interval 1.04-1.50) independent of eGFR. No significant interaction was observed between eGFR and leisure activity participation (P = 0.66).

conclusionsIn this study, leisure activity was associated with the risk of disability incidence independent of kidney function among community-dwelling older adults. These findings suggest that assessing leisure activity might be important for identifying the risk of disability in this population.

Indexed as

Glomerular Filtration RateIndependent LivingKidneyLeisure ActivitiesPersons with DisabilitiesAgedAged, 80 and overAge FactorsCreatinineDisability EvaluationFemaleHumansIncidenceJapanMaleRisk AssessmentCreatinineDisabilityKidney functionLeisure activitiesOlder adults

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.