Evidence map›Paper›PMID 40864295›Full record

SynthesisNeurosurgical review2025

Machine learning-based models and radiomics: can they be reliable predictors for meningioma recurrence? A systematic review and meta-analysis.

Behnaz Niroomand, Ibrahim Mohammadzadeh, Bardia Hajikarimloo, Mohammad Amin Habibi, Shahin Mohammadzadeh, Amir Mohammad Bahri, Mohammad Hassan Bagheri, Abdulrahman Albakr, Brij S Karmur, Hamid Borghei-Razavi

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Behnaz NiroomandSkull Base Research Center,, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-5184-7445
Ibrahim MohammadzadehSkull Base Research Center,, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Ibrahim.mdz7777@gmail.com.ORCID http://orcid.org/0000-0002-8862-0778
Bardia HajikarimlooDepartment of Neurological Surgery, University of Virginia, Charlottesville, VA, USA.
Mohammad Amin HabibiDepartment of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-7600-6925
Shahin MohammadzadehSkull Base Research Center,, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0009-0008-0644-1655
Amir Mohammad BahriStudent Research Committee, School of Medicine, Iran University of Medical Science, Tehran, Iran.ORCID http://orcid.org/0009-0003-0521-8420
Mohammad Hassan BagheriSchool of Medicine, Tehran University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0009-0000-5578-3215
Abdulrahman AlbakrDepartment of Neurological Surgery, Pauline Braathen Neurological Center, Cleveland Clinic Florida, Weston, FL, USA.
Brij S KarmurDepartment of Clinical Neurosciences, University of Calgary, Calgary, Canada.ORCID http://orcid.org/0000-0002-4224-173X
Hamid Borghei-RazaviDepartment of Neurological Surgery, Pauline Braathen Neurological Center, Cleveland Clinic Florida, Weston, FL, USA. borgheh2@ccf.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPredicting recurrence in meningioma patients is vital for improving long-term outcomes and tailoring personalized treatment strategies. While traditional diagnostic methods have advanced, accurately forecasting recurrence remains a persistent and critical challenge. This study explores the cutting-edge application of artificial intelligence (AI)-based models, which seamlessly integrate clinical, radiological, and pathological data, offering a transformative approach to enhancing the reliability and precision of recurrence prediction.

methodsEligible studies were identified through a comprehensive search of the Web of Science, Scopus, PubMed, and Embase databases. Extracted and synthesized metrics for analysis included accuracy, sensitivity, specificity, precision, F1 score, and area under the curve (AUC). Out of 2,971 studies screened, six met the inclusion criteria for systematic review, and three were included in the meta-analysis.

resultsThe pooled sensitivity and specificity of AI models were 0.86 [95% CI: 0.78-0.92] and 0.86 [95% CI: 0.81-0.90], respectively. The positive diagnostic likelihood ratio (DLR) was 6.33 [95% CI: 4.42-9.08], and the negative DLR was 0.16 [95% CI: 0.09-0.27]. The diagnostic odds ratio (DOR) was estimated at 40.11 [95% CI: 19.30-83.37], with a diagnostic score of 3.69 [95% CI: 2.96-4.42] and a pooled area under the curve (AUC) of 0.93 [95% CI: 0.90-0.95]. Subgroup analysis showed comparable sensitivity (RF: 0.88; LR: 0.84) and specificity (RF: 0.84; LR: 0.84) with no significant heterogeneity (I² = 0%).

conclusionsThese findings highlight the potential of AI-based models to predict meningioma recurrence, offer superior diagnostic accuracy, and aid clinical decision-making. Integrating clinical, radiological, and pathological data through AI-driven models demonstrates substantial promise in enhancing the reliability and efficiency of recurrence forecasting.

Indexed as

Machine LearningMeningeal NeoplasmsMeningiomaNeoplasm Recurrence, LocalHumansRadiomicsArtificial intelligenceDeep learningDiagnostic models, meningioma, recurrent, meta-analysisMachine learning

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.