Evidence map›Paper›PMID 40864274›Full record

ReviewAbdominal radiology (New York)2026

LI-RADS TRA V2024: innovations in imaging assessment of hepatocellular carcinoma response to locoregional therapies.

Alexandre Key Wakate Teruya, Joao Miranda, Hilton Leão Filho, Daniel Lahan-Martins, Cassia Tamura Sttefano Guimaraes, Roberto Blasbalg, Fernanda Garozzo Velloni

Abstract readReview
PubMed Publisher
In one paragraph

Review in Abdominal radiology (New York), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alexandre Key Wakate TeruyaDASA, São Paulo, Brazil. alexandre.teruya.ext@dasa.com.br.
Joao MirandaMayo Clinic, Rochester, United States. joaomirandamd@gmail.com.
Hilton Leão FilhoDASA, São Paulo, Brazil.
Daniel Lahan-MartinsDASA, São Paulo, Brazil.
Cassia Tamura Sttefano GuimaraesDASA, São Paulo, Brazil.
Roberto BlasbalgDASA, São Paulo, Brazil.
Fernanda Garozzo VelloniDASA, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Liver Imaging Reporting and Data System (LI-RADS) has become an essential tool for standardizing the detection, diagnosis, and treatment response assessment of hepatocellular carcinoma (HCC) using contrast-enhanced CT and MRI. With the rising incidence of HCC, the use of local-regional therapies (LRT) has also expanded. To address the increasing complexity of post-treatment imaging interpretation, the LI-RADS Treatment Response Assessment (TRA) algorithm was developed to provide a structured and reproducible approach for evaluating tumor response following various forms of LRT. However, imaging features following radiation-based therapies-such as transarterial radioembolization and stereotactic body radiation therapy-often differ from those seen after thermal ablation and transarterial chemoembolization. Recognizing these differences, the 2024 LI-RADS TRA update introduces refinements to improve diagnostic accuracy in this context. This review outlines the evolving role of LI-RADS in post-treatment assessment, highlights imaging findings associated with different LRTs, and explores ongoing refinements aimed at optimizing its clinical utility. Finally, we discuss the need for prospective validation of the new algorithm to confirm its diagnostic performance and clinical impact.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsRadiology Information SystemsTomography, X-Ray ComputedAlgorithmsChemoembolization, TherapeuticContrast MediaHumansMagnetic Resonance ImagingTreatment OutcomeContrast MediaHepatocellular carcinomaLiver imaging reporting and data systemLocoregional therapyTreatment response assessment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.