Evidence map›Paper›PMID 40864205›Full record

ArticleAnalytical and bioanalytical chemistry2025

Identification of serum N,N-dimethylglycine as a potential biomarker for prenatal diagnosis of congenital heart disease using

Baogang Xie, Dujuan Zhan, Le Wu, Lele Wang, Yongrong Lei, Meng Liu, Xiaodan Liu, Suping Li

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Baogang XieModern Industrial College of Traditional Chinese Medicine and Health, Lishui University, Lishui, 323000, China. xiebaogang99@lsu.edu.cn.ORCID http://orcid.org/0000-0002-0685-1346
Dujuan ZhanModern Industrial College of Traditional Chinese Medicine and Health, Lishui University, Lishui, 323000, China.
Le WuMedical College of Jiaxing University, Jiaxing University, Jiaxing, 314001, China.
Lele WangMedical College of Jiaxing University, Jiaxing University, Jiaxing, 314001, China.
Yongrong LeiModern Industrial College of Traditional Chinese Medicine and Health, Lishui University, Lishui, 323000, China.
Meng LiuModern Industrial College of Traditional Chinese Medicine and Health, Lishui University, Lishui, 323000, China.
Xiaodan LiuJiaxing Maternity and Child Health Care Hospital, Jiaxing University, Jiaxing, China. 80liuxiaodan@163.com.
Suping LiJiaxing Maternity and Child Health Care Hospital, Jiaxing University, Jiaxing, China. lilly2007@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital heart disease (CHD) poses significant clinical challenges due to limitations in early prenatal diagnosis. This study aimed to identify serum metabolic biomarkers for CHD using a combined metabolomics approach. Serum samples from 55 pregnant women carrying fetuses with confirmed CHD (CHDP group) and 49 healthy controls (ZCP group) were analyzed via non-targeted

Indexed as

Heart Defects, CongenitalMetabolomicsPrenatal DiagnosisSarcosineTandem Mass SpectrometryAdultBiomarkersCase-Control StudiesChromatography, High Pressure LiquidFemaleHumansLiquid Chromatography-Mass SpectrometryPregnancyProton Magnetic Resonance SpectroscopyBiomarkersdimethylglycineSarcosineBiomarkerCongenital heart diseaseMetabolomicsN,N-DimethylglycinePrenatal diagnosis

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.