Evidence map›Paper›PMID 40864166›Full record

ArticleAnalytical chemistry2025

AIRPred: A Deep Learning Model Predictor for Peptide Intensity Ratios in Cross-Linking Mass Spectrometry Improves Cross-Link Spectrum Matching.

Zehong Zhang, Mei Wu, Max Ruwolt, Ying Zhu, Pin-Lian Jiang, Diogo Borges Lima, Fan Liu

Abstract read
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zehong ZhangLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany.ORCID 0000-0003-1309-4395
Mei WuLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany.ORCID 0000-0002-2467-1402
Max RuwoltLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany.ORCID 0009-0000-7220-406X
Ying ZhuLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany.ORCID 0000-0003-4158-8093
Pin-Lian JiangLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany.ORCID 0009-0002-6945-613X
Diogo Borges LimaLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany.ORCID 0000-0001-6056-0825
Fan LiuLeibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP), Berlin 13125, Germany.ORCID 0000-0002-2358-549X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cross-linking mass spectrometry (XL-MS) is a powerful tool in structural proteomics, offering insights into protein conformations, interactions and dynamics by linking spatially proximal residues. However, current cross-linked spectrum match (CSM) scoring methods rely heavily on mass-to-charge ratio (

Indexed as

Cross-Linking ReagentsDeep LearningMass SpectrometryPeptidesProteomicsCross-Linking ReagentsPeptides

Identifiers

PMID40864166
PMCPMC12658862

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.