High Efficacy of Triclabendazole/Ivermectin Combination Compared to Triclabendazole Monotherapy for Treating Human Fascioliasis in Upper Egypt: A Prospective Study.

Waleed Attia Hassan, Haidi Karam-Allah Ramadan, Mona Gaber, Samia S Alkhalil, Alzahraa Abdelraouf Ahmad

Abstract read

In one paragraph

Article in Tropical medicine and infectious disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Waleed Attia HassanDepartment of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.ORCID 0000-0001-9429-1715

Haidi Karam-Allah RamadanDepartment of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.ORCID 0000-0003-0627-3985

Mona GaberDepartment of Medical Parasitology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.ORCID 0000-0002-1735-0168

Samia S AlkhalilDepartment of Medical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Alquwayiyah, Riyadh 11961, Saudi Arabia.ORCID 0000-0001-5811-7592

Alzahraa Abdelraouf AhmadDepartment of Medical Parasitology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.ORCID 0000-0002-2947-3122

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triclabendazole (TCBZ) is the gold standard treatment for fascioliasis. However, reports on resistance are increasing, emphasizing the need for alternative therapy. Combining TCBZ with ivermectin (IVM) was found to be effective for treating animal fascioliasis. Building on this, we aimed to evaluate the efficacy of the TCBZ/IVM combination therapy for human fascioliasis. This study enrolled 136 patients with

Indexed as

adjunctive treatmentcombination therapyhuman fascioliasisivermectintreatment failuretriclabendazole

Identifiers

PMID40864124

DOI10.3390/tropicalmed10080221

PMCPMC12389878

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.