Evidence map›Paper›PMID 40864060›Full record

ArticleToxins2025

Factors Influencing the Effectiveness of Botulinum Toxin Therapy in Bruxism Management.

Azusa Furuhata, Kazuya Yoshida, Shiroh Isono

Abstract read
In one paragraph

Article in Toxins, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Azusa FuruhataDepartment of Internal Medicine, Nippon Dental University, Tokyo 102-8158, Japan.ORCID 0009-0006-5252-5978
Kazuya YoshidaDepartment of Oral and Maxillofacial Surgery, National Hospital Organization, Kyoto Medical Center, Kyoto 612-8555, Japan.ORCID 0000-0002-2985-4347
Shiroh IsonoDepartment of Anesthesiology, Chiba University, Chiba 260-8677, Japan.ORCID 0000-0002-1875-6098

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A total of 304 patients with bruxism (206 women, 98 men; mean age: 52.5 years) received 25 units of botulinum toxin injected into the bilateral masseter muscles; the changes in various clinical symptoms and their contributing factors were analyzed 2 months after treatment. The mean masseter muscle electromyographic amplitude (189 μV) and maximal bite force (618.4 N) significantly decreased after botulinum toxin therapy compared to that at baseline (55.4 μV, 527.3 N, respectively;

Indexed as

Botulinum ToxinsBotulinum Toxins, Type ABruxismMasseter MuscleNeuromuscular AgentsAdultAgedBite ForceElectromyographyFemaleHumansMaleMiddle AgedTreatment OutcomeYoung AdultBotulinum ToxinsBotulinum Toxins, Type ANeuromuscular Agentsagingbite forcebotulinum neurotoxinbotulinum toxin therapybruxismelectromyographymasseter musclemuscle painsex differencesleep quality

Identifiers

PMID40864060
PMCPMC12389857

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.