Evidence map›Paper›PMID 40863984›Full record

ReviewNeurology international2025

Endovascular Treatment of Stroke and Anesthesia Technique: What Is the Best Approach, According to the Literature?

Federica Arturi, Gabriele Melegari, Fabio Gazzotti, Elisabetta Bertellini, Alberto Barbieri

Abstract readReview
In one paragraph

Review in Neurology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Federica ArturiSchool of Anaesthesia and Intensive Care, University of Modena and Reggio Emilia, Via del Pozzo 71, 4112 Modena, Italy.
Gabriele MelegariDepartment of Anaesthesia and Intensive Care, Azienda Ospedaliera Universitaria di Modena, Via del Pozzo 71, 4112 Modena, Italy.ORCID 0000-0003-4512-4835
Fabio GazzottiSchool of Anaesthesia and Intensive Care, University of Modena and Reggio Emilia, Via del Pozzo 71, 4112 Modena, Italy.
Elisabetta BertelliniSchool of Medicine, University of Modena and Reggio Emilia, Via del Pozzo 71, 4112 Modena, Italy.
Alberto BarbieriSchool of Anaesthesia and Intensive Care, University of Modena and Reggio Emilia, Via del Pozzo 71, 4112 Modena, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesEndovascular thrombectomy has become a mainstay in the treatment of acute ischemic stroke caused by large vessel occlusion. Among the multiple factors that influence outcomes, the choice of anesthetic technique-general anesthesia (GA), conscious sedation (CS), or local anesthesia (LA)-remains controversial. This narrative review aims to critically examine and synthesize current evidence comparing the efficacy and safety of different anesthetic strategies in endovascular stroke treatment.

methodsA structured search of the PubMed

resultsSeveral randomized controlled trials and observational studies show comparable functional outcomes between GA and CS, though CS may confer advantages in early neurological recovery and reduced complications. Local anesthesia, though less studied, may offer favorable outcomes in selected patients. General anesthesia appears to be associated with greater hemodynamic variability and a higher risk of post-procedural infections, particularly in unsuccessful interventions. Maintaining stable blood pressure and minimizing ventilation duration are crucial to improving patient prognosis.

conclusionsWhile both GA and CS are viable options during thrombectomy, CS and LA may provide a safer profile in selected patients by preserving hemodynamic stability and reducing infectious risk. Personalized anesthetic strategies and further high-quality trials are warranted.

Indexed as

blood pressure managementconscious sedationendovascular thrombectomygeneral anesthesiainfection riskischemic strokelocal anesthesianeurological outcomeperioperative carestroke

Identifiers

PMID40863984
PMCPMC12389025

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.