Evidence map›Paper›PMID 40863930›Full record

ArticleToxics2025

Embryonic Exposure to TPhP Elicits Osteotoxicity via Metabolic Disruption in

Melissa C Gronske, Jamie K Cochran, Jessika D Foland, Dereje Jima, David B Buchwalter, Heather M Stapleton, Seth W Kullman

Abstract read
In one paragraph

Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Melissa C GronskeComparative Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27695, USA.
Jamie K CochranToxicology Program, North Carolina State University, Raleigh, NC 27695, USA.
Jessika D FolandDepartment of Biological Sciences, North Carolina State University, Raleigh, NC 27695, USA.
Dereje JimaCenter for Human Health and the Environment, North Carolina State University, Raleigh, NC 27695, USA.
David B BuchwalterToxicology Program, North Carolina State University, Raleigh, NC 27695, USA.
Heather M StapletonNicholas School of the Environment, Duke University, Durham, NC 27710, USA.
Seth W KullmanComparative Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0002-6029-2266

Funding

Zebrafish as a Detector of Organophosphate ExposureP42ES010356 · NIEHS · DUKE UNIVERSITY · PI AMY H HERRING · 2000 to 2026
$56.2M
Translational Research Support CoreP30ES025128 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Sue Fenton · 2015 to 2026
$18.3M
TRAINING IN BIOCHEMICAL AND ENVIRONMENTAL TOXICOLOGYT32ES007046 · NIEHS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Seth William Kullman · 1985 to 2026
$5.1M
Interdisciplinary Biomedical Research Training ProgramT35OD011070 · OD · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Ronald Hak Long Li · 2012 to 2026
$1.1M
NIEHS NIH HHS P30 ES025128NIEHS NIH HHS P42 ES010356NIEHS NIH HHS T32 ES007046NIH HHS 1T32ES007046-44NIH HHS T35 OD011070
6 · The paper itself

Abstract

Triphenyl phosphate (TPhP) is a widely used organophosphate flame retardant and plasticizer, raising concerns over its health impacts. This study examined the effects of embryonic TPhP exposure on axial skeletal development and metabolism in medaka (

Indexed as

medakametabolic disruptionskeletal toxicitytriphenyl phosphate

Identifiers

PMID40863930
PMCPMC12390264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.