ArticleToxics2025
Children and Adolescents' Susceptibility to Domoic Acid in Southern China: Preliminary Evidence Revealing Baseline Exposure Profiles and Multidimensional Influencing Factors.
Article in Toxics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Domoic acid (DA) is a potent neurotoxin that poses public health concerns, especially for children and adolescents during critical neurodevelopmental periods. In the present study, urinary DA concentrations in 216 children and adolescents at the age of 6 to 18 in southern China were determined using a novel dansyl-chloride (DNS-Cl) derivatization high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method with ultrahigh sensitivity (LOQ: 0.087 ng/mL). The median urinary DA concentration was 2.17 ng/mL (interquartile range (IQR): 0.87-4.08 ng/mL). When analyzed by age group, the medians were 1.40 ng/mL (6-9 years; IQR: 0.55-3.49 ng/mL), 2.16 ng/mL (10-13 years; IQR: 0.94-4.07 ng/mL), and 2.93 ng/mL (14-18 years; IQR: 1.06-5.06 ng/mL). Our findings revealed that urinary DA concentrations increased with age and varied significantly across different body mass index groups (
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