Evidence map›Paper›PMID 40863842›Full record

ReviewNanomaterials (Basel, Switzerland)2025

Advancements in Tumor-Targeted Nanoparticles: Design Strategies and Multifunctional Therapeutic Approaches.

Mengya Li, Shengxi Zhou, Yan Zhang, Jingan Li, Kun Zhang

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mengya LiSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.ORCID 0009-0001-3717-8529
Shengxi ZhouSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Yan ZhangSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.
Jingan LiSchool of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China.ORCID 0000-0002-0305-6929
Kun ZhangSchool of Life Science, Zhengzhou University, Zhengzhou 450001, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer treatment faces significant challenges due to drug resistance, non-specific toxicity, and limited penetration of therapeutic agents. Here, we discuss the latest advancements in the design and application of tumor-targeted nanoparticles, focusing on polymer-based, biomimetic, and inorganic nanocarriers, as well as innovative surface modification strategies, to enhance diagnostic and therapeutic approaches in cancer treatment, including the co-delivery of chemotherapeutic agents with biologicals or photo/sonosensitizers for synergistic therapeutic effects. This review not only highlights the current importance of nanoparticle design and application for tumor targeting but also provides insights into future directions for more effective cancer therapies. By integrating advanced material science with biology, these strategies hold the potential to transform the landscape of cancer treatment, offering hope for improved patient outcomes and personalized therapeutic approaches.

Indexed as

diagnosisnanoparticlessurface modificationsynergistic therapeutic effects

Identifiers

PMID40863842
PMCPMC12388279

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.