Evidence map›Paper›PMID 40863793›Full record

ReviewNanomaterials (Basel, Switzerland)2025

Gold Nanoparticles for Wound Healing in Animal Models.

Stephen Klavsen, Sten Rasmussen

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Stephen KlavsenDepartment of Clinical Medicine, Aalborg University, 9260 Aalborg, Denmark.
Sten RasmussenDepartment of Clinical Medicine, Aalborg University, 9260 Aalborg, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGold nanoparticles (GNPs) are increasingly studied for their potential to enhance wound healing, but their overall efficacy remains uncertain.

methodsWe conducted a systematic meta-analysis (search date: 14 May 2025) across five databases. Included were randomized animal studies comparing GNPs to placebo, reporting wound closure percentages and relevant variance measures. Risk of bias was assessed using Cochrane and CAMARADES tools. Cohen's d was used to estimate effect size under a random-effects model.

resultsThirty-one studies met the inclusion criteria. The pooled effect size was d = 4.52 (95% CI: 3.61 to 5.43; z = 9.73;

conclusionGNPs significantly accelerate wound healing in animal models, supporting their potential as therapeutic agents.

Indexed as

full-thickness excisional woundsgold nanoparticlesmeta-analysisnanoparticle therapypreclinical animal modelssystematic reviewwound healing

Identifiers

PMID40863793
PMCPMC12388031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.