Evidence map›Paper›PMID 40863633›Full record

ArticleMarine drugs2025

Discovery of New Everninomicin Analogs from a Marine-Derived

Tae Hyun Lee, Nathan J Brittin, Imraan Alas, Christopher D Roberts, Shaurya Chanana, Doug R Braun, Spencer S Ericksen, Song Guo, Scott R Rajski, Tim S Bugni

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tae Hyun LeePharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI 53705, USA.
Nathan J BrittinPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0009-0004-4309-7735
Imraan AlasPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0001-9048-6742
Christopher D RobertsPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0003-0949-1320
Shaurya ChananaPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-3021-2210
Doug R BraunPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI 53705, USA.
Spencer S EricksenSmall Molecule Screening Facility, UW Carbone Cancer Center, Madison, WI 53792, USA.ORCID 0000-0003-4907-1160
Song GuoSmall Molecule Screening Facility, UW Carbone Cancer Center, Madison, WI 53792, USA.
Scott R RajskiPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-0238-8411
Tim S BugniPharmaceutical Sciences Division, University of Wisconsin-Madison, Madison, WI 53705, USA.ORCID 0000-0002-4502-3084

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI Christian Capitini · 1985 to 2026
$142.6M
Novel antimicrobials targeting MDR pathogens from animal microbial symbiontsU19AI142720 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI SAFDAR, NASIA · 2019 to 2023
$30.1M
NMR User Program at NMRFAMR24GM141526 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Katherine Anne Henzler-Wildman · 2021 to 2026
$6.4M
Chemistry-Biology Interface Training ProgramT32GM152341 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI Helen E. Blackwell · 2024 to 2026
$1.6M
National Institute of Allergy and Infectious Diseases U19AI142720NCI NIH HHS P30 CA014520NIAID NIH HHS U19 AI142720NIGMS NIH HHS R24 GM141526NIGMS NIH HHS R24GM141526NIGMS NIH HHS T32 GM152341
6 · The paper itself

Abstract

During the course of genome mining initiatives, we identified a marine-derived

Indexed as

Anti-Bacterial AgentsMicromonosporaAquatic OrganismsBiological ProductsDrug DiscoveryGenomicsMetabolomicsMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsTandem Mass SpectrometryAnti-Bacterial AgentsBiological Productsantibacterialgenome miningGlobal Natural Products Social molecular networking (GNPS)HCAPCAMicromonospora

Identifiers

PMID40863633
PMCPMC12387530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.