Evidence map›Paper›PMID 40863629›Full record

ArticleMarine drugs2025

Enhancing Fucoxanthin Pickering Emulsion Stability and Encapsulation with Seaweed Cellulose Nanofibrils Using High-Pressure Homogenization.

Ying Tuo, Mingrui Wang, Yiwei Yu, Yixiao Li, Xingyuan Hu, Long Wu, Zongpei Zhang, Hui Zhou, Xiang Li

Abstract read
In one paragraph

Article in Marine drugs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ying TuoCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.ORCID 0009-0008-4034-5202
Mingrui WangCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Yiwei YuCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Yixiao LiCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Xingyuan HuCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Long WuCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.ORCID 0000-0003-3786-6644
Zongpei ZhangQingdao Bright Moon Seaweed Group Co., Ltd., Qingdao 266499, China.
Hui ZhouCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.
Xiang LiCollege of Food Science and Engineering, Dalian Ocean University, Dalian 116023, China.

Funding

China Agriculture Research System No: CARS-50Collaborative Project of the Liaoning Provincial Science and Technology Program 2024JH2/102600080Liaoning Provincial Department of Education China JYTQN2023136Liaoning Provincial Natural Science Foundation LPNSFMS2025177Technology Foundation of the Dalian Jinshiwan Laboratory Dljswgj202404
6 · The paper itself

Abstract

Poor solubility and bioavailability have limited the application of fucoxanthin in drug and functional food processing. In order to encapsulate fucoxanthin in delivery systems, in this study, cellulose was isolated from industrial brown algae residues and high-pressure homogenized into cellulose nanofibrils (CNFs). Then, fucoxanthin was encapsulated into the Pickering emulsion stabilized by the CNFs. The effect of high-pressure homogenization on the characteristics of cellulose and the stability of fucoxanthin emulsion was evaluated. The results indicated that CNFs prepared at 105 MPa had a diameter of 87 nm and exhibited high zeta potential and thermal stability. Encapsulation efficiency peaked at 70.8% with 1.0 mg/mL fucoxanthin, and after three freeze-thaw cycles the encapsulation efficiency was higher than 60%. The DPPH scavenging activity after 12 days' storage at 4 °C was still 42%. Furthermore, the Pickering emulsion with 1.0 mg/mL fucoxanthin showed high stability and antioxidant activity under different pH values, salinity, temperature, and UV light exposure duration. The CNFs effectively protected fucoxanthin from degradation, offering a novel delivery system for marine bioactive compounds. To the best of our knowledge, this is the first study on the fucoxanthin delivery system of Pickering emulsion stabilized by the CNFs. Such emulsion might benefit the encapsulation and release of bioactive components in marine drugs.

Indexed as

CelluloseNanofibersSeaweedXanthophyllsAntioxidantsDrug CompoundingDrug StabilityEmulsionsHydrogen-Ion ConcentrationPressureSolubilityTemperatureAntioxidantsCelluloseEmulsionsfucoxanthinXanthophyllscellulose nanofibrilsencapsulationfucoxanthinPickering emulsionstability

Identifiers

PMID40863629
PMCPMC12387411

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.