Evidence map›Paper›PMID 40863327›Full record

ArticleJournal of xenobiotics2025

From Farmworkers to Urban Residents: Mapping Multi-Class Pesticide Exposure Gradients in Morocco via Urinary Biomonitoring.

Zineb Ben Khadda, Andrei-Flavius Radu, Souleiman El Balkhi, Fagroud Mustapha, Yahya El Karmoudi, Gabriela Bungau, Pierre Marquet, Tarik Sqalli Houssaini, Sanae Achour

Abstract read
In one paragraph

Article in Journal of xenobiotics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zineb Ben KhaddaLaboratory of Epidemiology and Research in Health Sciences, Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdellah University, Fez 30070, Morocco.ORCID 0009-0003-9516-3717
Andrei-Flavius RaduDoctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.ORCID 0000-0002-7625-8177
Souleiman El BalkhiDepartment of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, 87000 Limoges, France.
Fagroud MustaphaDepartment of Agronomy, National School of Agriculture, Meknes 50001, Morocco.
Yahya El KarmoudiLaboratory of Ecology, Systematics, and Conservation of Biodiversity, LESCB URL-CNRST N° 18, FS, Abdelmalek Essaadi University, Tetouan 93002, Morocco.ORCID 0009-0004-8020-3269
Gabriela BungauDoctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.
Pierre MarquetDepartment of Pharmacology, Toxicology and Pharmacovigilance, CHU Limoges, 87000 Limoges, France.
Tarik Sqalli HoussainiLaboratory of Epidemiology and Research in Health Sciences, Faculty of Medicine and Pharmacy, Sidi Mohammed Ben Abdellah University, Fez 30070, Morocco.ORCID 0000-0002-7388-288X
Sanae AchourLaboratory of Pharmacology and Toxicology, University Hospital Hassan II, Fez 30050, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pesticide exposure gradients between occupational, para-occupational, and general populations remain poorly characterized in North African agricultural contexts. This study evaluates urinary pesticide levels among farmers, indirectly exposed individuals, and a control group in Morocco's Fez-Meknes region. A cross-sectional survey measured pesticide concentrations using LC-MS/MS in urine samples collected from 154 adults residing in both rural and urban areas. A questionnaire was used to gather information from participants regarding factors that may elevate the risk of pesticide exposure. The results revealed that farmers exhibited the highest concentrations of pesticides in their urine, including compounds classified as Ia/Ib by the World Health Organization. Indirectly exposed individuals showed moderate levels of contamination, with notable detections such as dichlofluanid (22.13 µg/L), while the control group had residual traces of neonicotinoids, notably imidacloprid (2.05 µg/L). Multivariate analyses revealed several sociodemographic factors significantly associated with increased pesticide exposure. The main risk factors identified included low education, residence in an agricultural area, and the consumption of untreated water (wells/rivers). Conversely, wearing personal protective equipment was associated with reduced urinary concentrations. This study highlights intense occupational exposure among farmers, secondary environmental contamination among residents living near treated areas, and the widespread dispersion of pesticide residues into urban areas.

Indexed as

exposure risk factorsfarmersLC-MS/MSpesticide biomonitoringtoxicologyurinary biomonitoring

Identifiers

PMID40863327
PMCPMC12387287

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.