Evidence map›Paper›PMID 40863321›Full record

ArticleJournal of functional biomaterials2025

Comparative in Vitro Evaluation of Marginal Sealing in Class I Composite Restorations Using Fifth- and Seventh-Generation Adhesives.

Serban Talpos Niculescu, Ioana Veja, George-Dumitru Constantin, Ioana Elena Lile, Christos Armeniakos, Ioana Roxana Munteanu, Tareq Hajaj

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Serban Talpos NiculescuDepartment of Oral and Maxillofacial Surgery, Faculty of Dentistry, Victor Babes University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania.
Ioana VejaDepartment of Dental Medicine, Faculty of Dentistry, "Vasile Goldis" Western University of Arad, Str. Liviu Rebreanu 86, 310045 Arad, Romania.ORCID 0000-0002-4837-2693
George-Dumitru ConstantinDiscipline of Clinical Practical Skills, Department I Nursing, Faculty of Medicine, Victor Babes University of Medicine and Pharmacy, 300041 Timisoara, Romania.ORCID 0000-0003-2580-2432
Ioana Elena LileDepartment of Dental Medicine, Faculty of Dentistry, "Vasile Goldis" Western University of Arad, Str. Liviu Rebreanu 86, 310045 Arad, Romania.ORCID 0009-0003-6347-3497
Christos ArmeniakosDepartment of Prosthodontics, Aristotle University of Thessaloniki, 541 24 Thessaloniki, Greece.
Ioana Roxana MunteanuDepartment of Oral Rehabilitation and Dental Emergencies, Faculty of Dentistry, Victor Babes University of Medicine and Pharmacy, Eftimie Murgu Square No. 2, 300041 Timisoara, Romania.ORCID 0009-0007-4608-9409
Tareq HajajDepartment of Prostheses Technology and Dental Materials, Faculty of Dentistry, Victor Babes University of Medicine and Pharmacy, 2 Eftimie Murgu Sq., 300041 Timisoara, Romania.ORCID 0000-0002-7500-7181

Funding

"Victor Babes" University of Medicine and Pharmacy in Timisoara publication fee
6 · The paper itself

Abstract

backgroundA major challenge in adhesive dentistry, often leading to restoration failure, is microleakage. This in vitro comparative study was designed to assess microleakage at the tooth-composite interface. The investigation aimed to compare the sealing efficacy of two commonly used adhesive systems.

methodsStandardized Class I cavities were prepared on 20 extracted human molars and randomly divided into two groups (n = 10 each). Group A was treated with a fifth-generation total-etch adhesive (OptiBond™ Solo Plus, Kerr Corporation, Orange, CA, USA), and Group B received a seventh-generation self-etch adhesive (Adhese® Universal VivaPen®, Ivoclar Vivadent AG, Schaan, Liechtenstein). All restorations were completed using Herculite XRV composite resin. Microleakage was evaluated using dye penetration analysis after immersion in 2% methylene blue for 10 days, followed by longitudinal sectioning and microscopic measurement at 500× magnification.

resultsThe fifth-generation adhesive group showed a mean microleakage of 0.2503 ± 0.1921 mm, while the seventh-generation group recorded 0.2484 ± 0.1764 mm. Statistical analysis using an independent t-test revealed no significant difference between the groups (

conclusionsBoth adhesive systems demonstrated comparable performance in minimizing microleakage under standardized conditions. Although the total-etch group exhibited slightly lower numerical values, the difference was not statistically significant. These findings suggest that both adhesive approaches can be clinically effective when applied appropriately.

Indexed as

adhesive systemsbonding agentsclass I cavitycomposite restorationdental adhesivesdye penetrationmicroleakageself-etchtooth–restoration interfacetotal etch

Identifiers

PMID40863321
PMCPMC12387737

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.