Evidence map›Paper›PMID 40863245›Full record

ReviewDiseases (Basel, Switzerland)2025

Endobiliary Radiofrequency Ablation for Hepato-Biliary Diseases: A Narrative Review.

Tawfik Khoury, Wisam Sbeit, Andrea Lisotti, Bertrand Napoléon

Abstract readReview
In one paragraph

Review in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tawfik KhouryDepartment of Gastroenterology, Galilee Medical Center, Nahariya 22100, Israel.ORCID 0000-0001-6699-8625
Wisam SbeitDepartment of Gastroenterology, Galilee Medical Center, Nahariya 22100, Israel.ORCID 0000-0002-0921-4676
Andrea LisottiGastroenterology Unit, Hospital of Imola, University of Bologna, 33, 40126 Bologna, Italy.ORCID 0000-0002-7724-7402
Bertrand NapoléonDepartment of Gastroenterology, Hôpital Privé Jean Mermoz, Ramsay Santé, 69008 Lyon, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesMalignant biliary diseases still represent a therapeutic challenge given its poor prognosis, and limited response to the available curative treatments. Recently, endobiliary radiofrequency ablation (RFA) has been increasingly reported as an adjunct therapeutic option for biliary diseases, especially malignant biliary obstruction (MBO), due to potentially improving survival and stent patency.

methodsHerein, we provide a comprehensive review article discussing the indication, procedural details, safety, and comparative efficacy of endobiliary RFA to aid in providing an in-depth understanding of the clinical indications and future implications of this specific option.

resultsOverall, endobiliary RFA is technically feasible, being associated with a high safety profile, significantly improving biliary stent patency, and having a potential benefit in extending the survival of patients with MBO who were treated with endobiliary RFA combined with biliary stenting vs. stenting alone. Moreover, it has a promising role in the treatment of intraductal extension of ampullary tumors.

conclusionsEndobiliary RFA had a beneficial therapeutic effect in biliary strictures, with potential impact on patients outcome and survival.

Indexed as

biliaryefficacymalignantobstructionRFAsafety

Identifiers

PMID40863245
PMCPMC12386107

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.