Evidence map›Paper›PMID 40863238›Full record

ArticleDiseases (Basel, Switzerland)2025

Is There a Role for the Neutrophil-to-Lymphocyte Ratio for Rebleeding and Mortality Risk Prediction in Acute Variceal Bleeding? A Comparative 5-Year Retrospective Study.

Sergiu Marian Cazacu, Dragos Ovidiu Alexandru, Alexandru Valentin Popescu, Petrica Popa, Ion Rogoveanu, Vlad Florin Iovanescu

Abstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sergiu Marian CazacuGastroenterology Department, University of Medicine and Pharmacy Craiova, Emergency Clinical Hospital Craiova, 200642 Craiova, Romania.ORCID 0000-0001-9623-7683
Dragos Ovidiu AlexandruBiostatistics Department, University of Medicine and Pharmacy Craiova, Emergency Clinical Hospital Craiova, 200642 Craiova, Romania.ORCID 0000-0001-7578-8048
Alexandru Valentin PopescuGastroenterology Department, Emergency Clinical Hospital Craiova, 200642 Craiova, Romania.
Petrica PopaGastroenterology Department, University of Medicine and Pharmacy Craiova, Emergency Clinical Hospital Craiova, 200642 Craiova, Romania.ORCID 0000-0003-4452-0991
Ion RogoveanuGastroenterology Department, University of Medicine and Pharmacy Craiova, Emergency Clinical Hospital Craiova, 200642 Craiova, Romania.
Vlad Florin IovanescuGastroenterology Department, University of Medicine and Pharmacy Craiova, Emergency Clinical Hospital Craiova, 200642 Craiova, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Acute variceal bleeding (AVB) represents an important cause of upper gastrointestinal bleeding (UGIB). Several prognostic scores may be useful for assessing mortality and rebleeding risk, with the Glasgow-Blatchford score (GBS) and Rockall score being the most commonly used for non-variceal bleeding. Scores assessing liver failure (MELD and Child) do not reflect bleeding severity. The neutrophil-to-lymphocyte ratio (NLR) increases in UGIB and can predict survival and rebleeding. (2) Methods: We analyzed the predictive role of NLR, GBS, Rockall, AIMS65, Child, and MELD for mortality (48 h, 5-day, in-hospital, and 6-week) and rebleeding in AVB patients admitted to our hospital from 2017 to 2021. ROC analysis was performed, and a multivariate analysis with logistic regression was used to construct a simplified model. (3) Results: A total of 415 patients were admitted. NLR exhibited fair accuracy for 48-h mortality (AUC 0.718, 95% CI 0.597-0.839,

Indexed as

acute variceal bleedingChild-Turcotte-Pugh scoreMELDneutrophil-to-lymphocyte ratioprognostic scoresupper gastrointestinal bleeding

Identifiers

PMID40863238
PMCPMC12385447

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.