A Sensitive Sandwich-Type Electrochemical Immunosensor for Carbohydrate Antigen 19-9 Based on Covalent Organic Frameworks.

Ting Wu, Rongfang Chen, Yaqin Duan, Longfei Miao, Yongmei Zhu, Li Wang

Abstract read

In one paragraph

Article in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ting WuCollege of Chemistry and Materials, Jiangxi Normal University, Nanchang 330022, China.

Rongfang ChenCollege of Chemistry and Materials, Jiangxi Normal University, Nanchang 330022, China.

Yaqin DuanCollege of Chemistry and Materials, Jiangxi Normal University, Nanchang 330022, China.

Longfei MiaoCollege of Chemistry and Materials, Jiangxi Normal University, Nanchang 330022, China.ORCID 0009-0001-9860-5088

Yongmei ZhuCollege of Chemistry and Materials, Jiangxi Normal University, Nanchang 330022, China.

Li WangCollege of Chemistry and Materials, Jiangxi Normal University, Nanchang 330022, China.ORCID 0000-0003-0510-7985

Funding

Early Career Young Scientific and Technological Development Project of Jiangxi Province 20244BCE52015Graduate Student Innovation Fund of Jiangxi Provincial Department of Education YJS2024024The Doctoral Start-up Funding of Jiangxi Normal University NO NUMBER

6 · The paper itself

Abstract

Since carbohydrate antigen 19-9 (CA 19-9) is a significant biomarker for the clinical diagnosis and treatment of pancreatic cancer, a sensitive sandwich-type immunosensor was proposed with an epoxy functionalized covalent organic framework (EP-COF

Indexed as

Biosensing TechniquesCA-19-9 AntigenElectrochemical TechniquesMetal-Organic FrameworksBiomarkers, TumorGoldHumansImmunoassayLimit of DetectionMetal NanoparticlesBiomarkers, TumorCA-19-9 AntigenGoldMetal-Organic Frameworkscarbohydrate antigen 19-9covalent organic frameworkselectrochemical immunosensorsignal amplification strategy

Identifiers

PMID40862953

DOI10.3390/bios15080492

PMCPMC12384156

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.