Evidence map›Paper›PMID 40862952›Full record

ReviewBiosensors2025

Capacitive Sensors for Label-Free Detection in High-Ionic-Strength Bodily Fluids: A Review.

Seerat Sekhon, Richard Bayford, Andreas Demosthenous

Abstract readReview
In one paragraph

Review in Biosensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Seerat SekhonDepartment of Electronic & Electrical Engineering, University College London, London WC1E 6BT, UK.ORCID 0009-0004-6322-9037
Richard BayfordDepartment of Natural Sciences, Middlesex University, London NW4 4BT, UK.ORCID 0000-0001-8863-6385
Andreas DemosthenousDepartment of Electronic & Electrical Engineering, University College London, London WC1E 6BT, UK.ORCID 0000-0003-0623-963X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Capacitive sensors are platforms that enable label-free, real-time detection at low non-perturbing voltages. These sensors do not rely on Faradaic processes, thereby eliminating the need for redox-active species and simplifying system integration for point-of-care diagnostics. However, their sensitivity in high-ionic-strength solutions, such as bodily fluids, is limited due to a reduced Debye length and non-specific interactions. The present review highlights advances in material integration, surface modification, and signal enhancement techniques to mitigate the challenges of deploying capacitive sensors in biofluids (sweat, saliva, blood, serum). This work further expands on the promise of such sensors for advancing liquid biopsies and highlights key technical challenges in translating capacitive systems to clinics.

Indexed as

Biosensing TechniquesBody FluidsElectric CapacitanceHumansPoint-of-Care Systemscapacitive biosensingdebye length limitationelectrochemical impedance spectroscopy (EIS)label-free detectionsurface functionalization

Identifiers

PMID40862952
PMCPMC12384789

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.