ArticleCurrent oncology (Toronto, Ont.)2025
Impact of Postoperative Infection on Lower Limb Function After Surgery for Malignant Bone and Soft Tissue Tumors: Data from a Nationwide Registry in Japan.
Article in Current oncology (Toronto, Ont.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Historical contributions and future horizons of Japanese orthopaedic oncology: from surgical innovation to nationwide collaborations.International orthopaedics · 2026Article
- Association between postoperative surgical site infection and oncologic outcomes in soft tissue sarcoma: a propensity score-matched analysis using the bone and soft tissue registry.International orthopaedics · 2026Article
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5 authors.
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Abstract
backgroundDue to the scarcity of cases, adjustments for confounding factors in analyses of the effects of postoperative infections on limb function after surgery for malignant bone and soft tissue tumors were insufficient in previous studies. One solution is to use big data from a nationwide registry.
methodsData from the Bone and Soft Tissue Tumor Registry in Japan were used to examine the impact of postoperative infections on limb function after surgery for malignant bone and soft tissue tumors in the lower extremities. Limb function was evaluated using the Musculoskeletal Tumor Society (MSTS) score.
resultsA total of 1099 soft tissue tumors and 410 bone tumor cases were included. Propensity score matching (PSM) was performed using significant factors in the propensity score logistic regression. After PSM, only "function" and "emotional acceptance" scores worsened in infection cases in the bone tumor group, while total MSTS scores remained unaffected in both the bone and soft tissue tumor groups. No subcategory scores worsened in the soft tissue tumor group.
conclusionsOur findings suggest that postoperative infections might not affect function in cases of soft tissue tumors and have only a limited impact in cases of bone tumors.
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