Evidence map›Paper›PMID 40862759›Full record

ReviewCells2025

The Yin and Yang of Heartbeats: Magnesium-Calcium Antagonism Is Essential for Cardiac Excitation-Contraction Coupling.

Chiara Marabelli, Demetrio J Santiago, Silvia G Priori

Abstract readReview
In one paragraph

Review in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. An Alkaloid from MarinePharmaceuticals (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chiara MarabelliDepartment of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-6613-4306
Demetrio J SantiagoCentro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), 28029 Madrid, Spain.ORCID 0000-0002-1541-8034
Silvia G PrioriDepartment of Molecular Medicine, University of Pavia, 27100 Pavia, Italy.

Funding

Fondazione Telethon ETS Italy GMR24T1117
6 · The paper itself

Abstract

While calcium (Ca

Indexed as

CalciumExcitation Contraction CouplingMagnesiumAnimalsHumansRyanodine Receptor Calcium Release ChannelCalciumMagnesiumRyanodine Receptor Calcium Release Channelcalcium-induced calcium releasecalcium signalingcardiac electrophysiologyexcitation–contraction couplingion channelsmagnesium

Identifiers

PMID40862759
PMCPMC12384121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.