Evidence map›Paper›PMID 40862740›Full record

ArticleCells2025

Disrupted Myelination in FAHN: Insights from a Patient-Specific hiPSC Neuron-Oligodendrocyte Model.

Fatima Efendic, Andreas Hermann, Moritz J Frech

Abstract read
In one paragraph

Article in Cells, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fatima EfendicTranslational Neurodegeneration Section "Albrecht Kossel", Department of Neurology, University Medical Center Rostock, 18147 Rostock, Germany.ORCID 0000-0002-8462-0690
Andreas HermannTranslational Neurodegeneration Section "Albrecht Kossel", Department of Neurology, University Medical Center Rostock, 18147 Rostock, Germany.ORCID 0000-0002-7364-7791
Moritz J FrechTranslational Neurodegeneration Section "Albrecht Kossel", Department of Neurology, University Medical Center Rostock, 18147 Rostock, Germany.ORCID 0000-0003-2421-8779

Funding

Hermann und Lilly Schilling-Stiftung für medizinische For-schung im Stifterverband not applicableNBIA Disorders association. not applicableProfessorinnenprogramm III University Rostock not applicable
6 · The paper itself

Abstract

Fatty-acid-hydroxylase-associated neurodegeneration (FAHN) is a rare neurodegenerative disorder caused by loss-of-function mutations in the

Indexed as

Induced Pluripotent Stem CellsMixed Function OxygenasesModels, BiologicalMyelin SheathNeurodegenerative DiseasesNeuronsOligodendrogliaAutophagyCoculture TechniquesHumansMutationMixed Function OxygenasesautophagydemyelinationFA2HFAHNinduced pluripotent stem cellsmyelin proteinsneuronsoligodendrocytes

Identifiers

PMID40862740
PMCPMC12384766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.