Evidence map›Paper›PMID 40862594›Full record

ArticleJournal of clinical microbiology2025

Comparison of core genome multi-locus sequencing typing pipelines for hospital outbreak detection of common bacterial pathogens.

Heather L Glasgow, Ying Zheng, Jessica N Brazelton, Li Tang, Randall T Hayden

Abstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Antibiotics (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Heather L GlasgowPathology Department, St. Jude Children's Research Hospital, , Memphis, Tennessee, USA.ORCID 0000-0002-6594-9837
Ying ZhengBiostatistics Department, St. Jude Children's Research Hospital, , Memphis, Tennessee, USA.
Jessica N BrazeltonPathology Department, St. Jude Children's Research Hospital, , Memphis, Tennessee, USA.
Li TangBiostatistics Department, St. Jude Children's Research Hospital, , Memphis, Tennessee, USA.
Randall T HaydenPathology Department, St. Jude Children's Research Hospital, , Memphis, Tennessee, USA.ORCID 0000-0002-3073-4115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial whole genome sequencing (WGS)-based methods have replaced conventional methods for genomic relatedness analysis in the investigation of or surveillance for infectious outbreaks. Analysis of WGS by core genome multi-locus sequence typing (cgMLST) has been proposed for standardized strain comparisons at high resolution and for longitudinal outbreak surveillance. We compared three commercial cgMLST software pipelines, Ridom SeqSphere+, 1928 Diagnostics' platform, and Ares Genetics ARESdb, for the identification of related (clustered) strains among 255 isolates of common bacterial pathogens, including

Indexed as

BacteriaBacterial InfectionsCross InfectionDisease OutbreaksGenome, BacterialMultilocus Sequence TypingHospitalsHumansMolecular EpidemiologySoftwareWhole Genome Sequencingbacterial relatednesscore genome multi-locus sequence typingoutbreak detectionoutbreak surveillancestrain typingwhole genome sequencing

Identifiers

PMID40862594
PMCPMC12506026

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.