Evidence map›Paper›PMID 40862592›Full record

ArticleMicrobiology spectrum2025

Development of a rapid and sensitive RPA-CRISPR/Cas12a-based assay for the detection of

Yu Shen, Chenchen Yi, Heng Wang, Yi Tang, Jun Li

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu ShenHangzhou Center for Disease Control and Prevention (Hangzhou Health Supervision Institution), Hangzhou, China.ORCID 0009-0008-0864-6558
Chenchen YiCenter of Reproductive Medicine, Sir Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Heng WangHangzhou Center for Disease Control and Prevention (Hangzhou Health Supervision Institution), Hangzhou, China.
Yi TangHangzhou Center for Disease Control and Prevention (Hangzhou Health Supervision Institution), Hangzhou, China.
Jun LiHangzhou Center for Disease Control and Prevention (Hangzhou Health Supervision Institution), Hangzhou, China.ORCID 0009-0002-4497-9305

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brucellosis, a zoonotic disease caused by

Indexed as

Brucella melitensisBrucellosisCRISPR-Cas SystemsMolecular Diagnostic TechniquesNucleic Acid Amplification TechniquesBacterial ProteinsCRISPR-Associated ProteinsEndodeoxyribonucleasesHumansLimit of DetectionRecombinasesReproducibility of ResultsSensitivity and SpecificityBacterial ProteinsCas12a proteinCRISPR-Associated ProteinsEndodeoxyribonucleasesRecombinasesBrucellaCRISPR/Cas12adiagnosisRPA

Identifiers

PMID40862592
PMCPMC12502682

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.