Evidence map›Paper›PMID 40862488›Full record

SynthesisInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2026

Non-pharmacologic therapies for treating sexual dysfunction during pregnancy: A systematic review and meta-analysis.

Antonio Carlos Queiroz de Aquino, Ayane Cristine Alves Sarmento, Ana Carolina Zimmermann Simões, Heitor Dutra de Medeiros, Beatriz Bomtempo de Siqueira, Tâmilly Batista Nascimento, Cijara Leonice de Freitas, Megan L Falsetta, Ana Katherine Gonçalves

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Antonio Carlos Queiroz de AquinoHealth Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.ORCID https://orcid.org/0000-0002-1464-243X
Ayane Cristine Alves SarmentoHealth Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.ORCID https://orcid.org/0000-0001-9131-1952
Ana Carolina Zimmermann SimõesSciences Applied to Women's Health Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.ORCID https://orcid.org/0000-0002-2296-2484
Heitor Dutra de MedeirosSchool of Health, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.
Beatriz Bomtempo de SiqueiraSchool of Health, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.
Tâmilly Batista NascimentoSchool of Health, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.
Cijara Leonice de FreitasHealth Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.
Megan L FalsettaDepartments of Obstetrics and Gynecology and Pharmacology and Physiology, University of Rochester Medical Center, Rochester, New York, USA.ORCID https://orcid.org/0000-0001-6341-3791
Ana Katherine GonçalvesHealth Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal, Rio Grande do Norte, Brazil.ORCID https://orcid.org/0000-0002-8351-5119

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSexual dysfunction during pregnancy is a common problem, and can occur as the result of various physical, hormonal, and emotional changes that women experience during this period. Non-pharmacologic treatments are recommended due to the restrictions on medications during this period.

objectivesTo summarize the evidence on non-pharmacologic interventions for treating sexual dysfunction during pregnancy. SEARCH STRATEGY: Searches were conducted in PubMed, Scopus, Web of Science, Embase, PsycINFO, PEDro, the Cochrane Central Register of Controlled Trials, and ClinicalTrials.gov. SELECTION CRITERIA: We included randomized clinical trials comparing interventions for treating sexual dysfunction during pregnancy. DATA COLLECTION AND ANALYSIS: From these search results, studies were selected, and data was extracted by two authors independently. The risk of bias was assessed using the Cochrane Risk of Bias tool (RoB 2.0). RevMan 5.4. was used for data synthesis. The Grading of Recommendations Assessment Development (GRADE) and Evaluation method was used to evaluate the strength of the evidence. MAIN

resultsWe retrieved a total of 9017 articles. Twenty-four studies met the eligibility criteria and were included in the systematic review, and nine studies were included in the meta-analysis. The total number of participants was 1557, with a mean age ranging from 19.3 to 30.7 years and a gestation ranging from 8.9 to 28.3 weeks. Patients undergoing cognitive behavioral therapy (CBT) had a mean increase of 6.82 in their Female Sexual Function Index (FSFI) total score (range 1.63-12.01, P = 0.010, I

conclusionCBT, the PLISSIT model, and sexual education for pregnant women can improve sexual function during the gestational period.

Indexed as

Pregnancy ComplicationsSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalCognitive Behavioral TherapyFemaleHumansPregnancyRandomized Controlled Trials as Topicmeta‐analysispregnancysexual dysfunctionsystematic reviewtherapeutics

Identifiers

PMID40862488
PMCPMC12936644

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.