Evidence map›Paper›PMID 40862351›Full record

ArticleMicrobiology resource announcements2025

BK polyomavirus genotype IV isolates from virus-specific T-cell therapy recipients.

Tiana A Walder, Heidi L Meeds, Michael S Grimley, Steven B Kleiboeker, Assem Ziady, Anthony Sabulski, Sonata Jodele, Alix E Seif, Stella M Davies, Benjamin L Laskin and 2 more

Abstract read
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In one paragraph

Article in Microbiology resource announcements, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Tiana A WalderDivision of Gastroenterology and Hepatology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0009-0003-5545-4675
Heidi L MeedsDivision of Gastroenterology and Hepatology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.
Michael S GrimleyDivision of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Steven B KleiboekerEurofins Viracor Laboratories, Lenexa, Kansas, USA.
Assem ZiadyDivision of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Anthony SabulskiDivision of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Sonata JodeleDivision of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Alix E SeifPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Stella M DaviesDivision of Bone Marrow Transplantation and Immune Deficiency, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Benjamin L LaskinPerelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Jason T BlackardDivision of Gastroenterology and Hepatology, College of Medicine, University of Cincinnati, Cincinnati, Ohio, USA.ORCID 0000-0003-2876-3811
Jeremy D RubinsteinDivision of Oncology, Cancer and Blood Diseases Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Funding

Viral and host predictors of BK polyomavirus associated hemorrhagic cystitisR01DK125418 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI BLACKARD, JASON T, LASKIN, BENJAMIN LEWIS · 2020 to 2024
$3.4M
Initiators of thrombotic microangiopathyR01HL171046 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI JASON T BLACKARD, Sonata Jodele · 2024 to 2026
$2.0M
Allogeneic virus-specific T-cell therapy after hematopoietic stem cell transplant: determinants of treatment success and failureR01HL169242 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Jeremy D Rubinstein · 2024 to 2026
$2.0M
NHLBI NIH HHS R01 HL169242NHLBI NIH HHS R01 HL171046NIDDK NIH HHS R01 DK125418
6 · The paper itself

Abstract

BK polyomavirus (BKPyV) can cause disease in transplant recipients. Virus-specific T-cell (VST) therapy is effective in decreasing virus levels in many individuals. BKPyV genetic variation can impact replication kinetics and immune responses. Here, we present the near full-length BKPyV genome sequences from two VST recipients in which genotype IV was isolated.

Indexed as

BK polyomavirusgenotypetransplantationviral diversityvirus-specific T-cell therapy

Identifiers

PMID40862351
PMCPMC12509543

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.