Evidence map›Paper›PMID 40862272›Full record

ArticleJournal of medical extended reality2025

AMXRA Guidelines on Extended Reality (XR) and Children: Considerations for Safe and Effective Application Development and Use.

Asher Marks, Veronica Weser, Thomas Jon Caruso, Susan Persky, Abraham Homer, Jeffrey Gold, Erin Williamson, Kimberly Hieftje

Abstract read
In one paragraph

Article in Journal of medical extended reality, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Asher MarksYale School of Medicine, Department of Pediatrics; The Yale Center for Immersive Technologies in Pediatrics, New Haven, CT, 06510.
Veronica WeserYale School of Medicine, Department of Pediatrics; The Yale Center for Immersive Technologies in Pediatrics, New Haven, CT, 06510.
Thomas Jon CarusoStanford University School of Medicine, Division of Pediatric Anesthesiology, Palo Alto, CA, 94304.
Susan PerskySocial and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, MD 20892.
Abraham HomerChildren's Hospital Colorado, Aurora, CO, 80045.
Jeffrey GoldKeck School of Medicine, University of Southern California, Departments of Anesthesiology, Pediatrics, and Psychiatry & Behavioral Sciences; The Saban Research Institute at Children's Hospital Los Angeles, Department of Anesthesiology Critical Care Medicine, The Biobehavioral Pain Lab, Los Angeles, CA 90033.
Erin WilliamsonLove146, New Haven, CT 06510.
Kimberly HieftjeYale School of Medicine, Department of Pediatrics; The Yale Center for Immersive Technologies in Pediatrics, New Haven, CT, 06510.

Funding

Immersive technologies in health and medicineZIAHG200423 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI PERSKY, SUSAN · 2024 to 2025
$237k
Intramural NIH HHS ZIA HG200423
6 · The paper itself

Abstract

The extended reality (XR) revolution has ushered in the adoption of head-mounted displays (HMDs), including among children. While well-studied clinical uses of XR hold promise for positive outcomes in pain management, behavioral change, and social connection, unsupervised use and improper implementation of immersive technologies in young populations raise significant concerns. Current age limit recommendations are based primarily on privacy laws and fail to address the potential physical, cognitive, emotional, and other psychosocial implications of XR for children. Commercially available HMDs are ill-suited for young users, leading to discomfort and suboptimal immersive experiences. Further, XR experiences challenge young children's ability to differentiate reality from fantasy, resulting in safety hazards and the potential for confabulated memories. Concerns extend to immersive social experiences, where the impact on mental health and safety is not yet fully understood. While acknowledging the risks, embracing XR technologies with thoughtful consideration is necessary to maximize their potential benefits for all youth, especially those facing adversity and isolation. Balancing accessibility and safety are essential as current and future XR technologies become integrated into children's daily lives. This manuscript represents AMXRA's official position on the responsible use of XR in children and will address the three major components of childhood development - physical, cognitive, and psychosocial - as they relate to the use and development of immersive technologies, in homes, schools, and clinics.

Indexed as

child developmentextended reality (XR)healthsafetyvirtual reality (VR)

Identifiers

PMID40862272
PMCPMC12373118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.