Evidence map›Paper›PMID 40862266›Full record

ArticleJournal of multidisciplinary healthcare2025

Research Trends and Hotspots of Gut Microbiota and Its Metabolites in Cardiovascular Diseases: A Bibliometric Analysis.

Kaixuan Zhang, Yajun Shi, Lirong Peng, Xiaofei Zhang, Nanbo Zheng, Jiajing Xin, Junbo Zou, Fei Luan

Abstract read
In one paragraph

Article in Journal of multidisciplinary healthcare, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kaixuan ZhangShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, 712046, People's Republic of China.
Yajun ShiShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, 712046, People's Republic of China.
Lirong PengDepartment of Pharmacy, Xi'an Central Hospital, Xi'an, Shaanxi, 710000, People's Republic of China.
Xiaofei ZhangShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, 712046, People's Republic of China.
Nanbo ZhengDepartment of Pharmacy, Xi'an Central Hospital, Xi'an, Shaanxi, 710000, People's Republic of China.
Jiajing XinShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, 712046, People's Republic of China.
Junbo ZouShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, 712046, People's Republic of China.ORCID 0000-0002-1651-4722
Fei LuanShaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an, 712046, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study leverages quantitative analysis to delve into the current state, key focal points, and developmental trajectory of research on gut microbiota and its metabolites in relation to cardiovascular diseases, offering guidance for future exploration. Methods: Utilizing software tools such as VOSviewer, CiteSpace, and Scimago Graphica, we conducted a multidimensional analysis. This analysis aimed to accurately evaluate the current research landscape and emerging focal points in the field of gut microbiota and cardiovascular disease research, both domestically and internationally. Moreover, it also uncovers the future trends of gut microbiota in cardiovascular disease research. Results: We included 4,348 articles and reviews examining the relationship between gut microbiota and cardiovascular diseases. Researchers from 105 countries and regions, 4,411 institutions, and 20,600 authors have contributed to this field. Key research topics include the Mediterranean diet, gut microbiota metabolites, coronary heart disease, myocardial infarction, atherosclerosis, probiotics, and prebiotics. Recently, there has been a significant increase in the frequency of specific keywords such as bile acid, trimethylamine oxide, and coronary artery disease. Conclusion: This study underscores the promising research prospects of gut microbiota and its metabolites in cardiovascular disease research. Their potential application value is expected to promote the sustainable development and innovation of related fields.

Indexed as

bibliometric analysiscardiovascular diseasesCiteSpacegut microbiotaresearch trendsVOSviewer

Identifiers

PMID40862266
PMCPMC12377372

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.