Evidence map›Paper›PMID 40862221›Full record

ArticleHemaSphere2025

Mesenchymal stromal cells from

Alessandra Ferrelli, Syed Mian, Marion Piganeau, Hector Huerga Encabo, Despoina Papazoglou, Giuseppe D'Agostino, Fatihah Mohamad Nor, Manuel Garcia-Albornoz, Steven Ngo, Linda Ariza-McNaughton and 5 more

Abstract read
In one paragraph

Article in HemaSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alessandra FerrelliHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Syed MianHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Marion PiganeauHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Hector Huerga EncaboHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Despoina PapazoglouHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Giuseppe D'AgostinoHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Fatihah Mohamad NorHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Manuel Garcia-AlbornozHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Steven NgoHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Linda Ariza-McNaughtonHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.
Erika MorsiaDepartment of Clinical and Molecular Sciences Università Politecnica della Marche Ancona Italy.
Matteo Giovanni Della PortaDepartment of Biomedical Sciences Humanitas University Milan Italy.
Claire HarrisonSchool of Cancer and Pharmaceutical Sciences King's College London London UK.ORCID https://orcid.org/0000-0002-3212-920X
Shahram KordastiSchool of Cancer and Pharmaceutical Sciences King's College London London UK.ORCID https://orcid.org/0000-0002-0347-4207
Dominique BonnetHaematopoietic Stem Cell Laboratory The Francis Crick Institute London UK.ORCID https://orcid.org/0000-0002-4735-5226

Funding

Wellcome Trust CC2027
6 · The paper itself

Abstract

Myeloproliferative Neoplasms (MPN) are malignancies of hematopoietic stem and progenitor cells (HSPCs) that lead to the overproduction of mature blood cells. These disorders include Essential Thrombocythemia (ET), Polycythemia Vera (PV), and Primary Myelofibrosis (PMF), primarily driven by somatic mutations such as

Identifiers

PMID40862221
PMCPMC12374162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.