ArticleFrontiers in endocrinology2025
Correlation between semen quality and the seminal biochemical markers: alpha-glucosidase, fructose, and zinc in infertile men compared with a normal population of men.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- DCDC2C Protein Expression in Human Spermatozoa: A Potential Molecular Marker for Asthenozoospermia.Medical sciences (Basel, Switzerland) · 2026Article
- Metals/Metalloids Profile in Seminal Plasma/Serum of Patients with Asthenozoospermia/Oligozoospermia: Correlation with Semen Quality.Biological trace element research · 2026Article
- Oxidative Stress and Inflammatory Biomarkers in Male Infertility: A Narrative Review of Diagnostic Value and Clinical Integration.Diagnostics (Basel, Switzerland) · 2026Review
- Research progress on the multidimensional mechanisms underlying impaired spermatogenesis induced by pathological microenvironment remodeling in chronic prostatitis.Frontiers in immunology · 2026Review
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Authors and funding
11 authors.
Funding
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Abstract
Introduction: The male reproductive tract's accessory glands produce seminal biochemical markers that can help diagnose reproductive disorders and assess male fertility. This study evaluated the relationship between seminal biochemical components and sperm parameters in 150 men, including 20 normospermic individuals and 130 infertile patients classified into oligozoospermia, azoospermia, asthenozoospermia, teratozoospermia, and oligoasthenoteratozoospermia (OAT) groups. Methods: The patients underwent semen analysis and measurements of fructose, neutral alpha-glucosidase (NAG) and zinc in seminal plasma. Results and discussions: The level of fructose was significantly decreased in asthenozoospermic and increased in oligoasthenoteratozoospermic (OAT) men. It was significantly correlated with semen volume, sperm concentration, progressive motility and morphology. Seminal neutral -glucosidase and zinc levels were found significantly reduced in azoospermic and OAT patients. The seminal NAG levels were significantly correlated with semen volume and progressive motility. For zinc level, the concentration was significantly correlated with sperm concentration (r = 0.041, p < 0.001).
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