Evidence map›Paper›PMID 40862110›Full record

ReviewFrontiers in endocrinology2025

Primary congenital hypothyroidism: a clinical review.

Paolo Cavarzere, Valentina Mancioppi, Riccardo Battiston, Valentina Lupieri, Anita Morandi, Claudio Maffeis

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Observational
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Paolo CavarzereDepartment of Mother and Child, Pediatric Unit B, University Hospital of Verona, Verona, Italy.
Valentina MancioppiDepartment of Mother and Child, Pediatric Unit B, University Hospital of Verona, Verona, Italy.
Riccardo BattistonDepartment of Mother and Child, Pediatric Unit B, University Hospital of Verona, Verona, Italy.
Valentina LupieriDepartment of Mother and Child, Pediatric Unit B, University Hospital of Verona, Verona, Italy.
Anita MorandiDepartment of Mother and Child, Pediatric Unit B, University Hospital of Verona, Verona, Italy.
Claudio MaffeisDepartment of Mother and Child, Pediatric Unit B, University Hospital of Verona, Verona, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital hypothyroidism (CH) is the most common neonatal endocrine disorder. It is one of the clinical conditions that has benefited most from the introduction of newborn screening 50 years ago, as clinical management has changed and long-term consequences have been significantly reduced. In areas where neonatal screening is active, most affected patients show a clinically normal phenotype and/or only mild symptoms. At the same time, thanks to a progressive reduction in the TSH level used as cut-off for neonatal screening, the number of cases of CH with gland

Indexed as

Congenital HypothyroidismHumansInfant, NewbornNeonatal ScreeningThyroxineThyroxinecongenital hypothyroidismdysgenesisdyshormonogenesisnewborn screening for congenital hypothyroidismthyroid gland

Identifiers

PMID40862110
PMCPMC12371337

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.