Primary cardiac angiosarcoma - a diagnostic roller-coaster till fatality.

Bhupendra Kumar Sihag, Ajay Bahl, Sarthak Wadhera, Arnav Aggarwal, Mohsin Raj Mantoo, Atit A Gawalkar

Abstract readCase Reports

In one paragraph

Article in Journal of cardiovascular and thoracic research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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5 · Who and what money

Authors and funding

6 authors.

Bhupendra Kumar SihagDepartment of Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0001-7068-8822

Ajay BahlDepartment of Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Sarthak WadheraDepartment of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Arnav AggarwalDepartment of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Mohsin Raj MantooDepartment of Cardiology, All India Institute of Medical Sciences, New Delhi, India.

Atit A GawalkarDepartment of Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.ORCID https://orcid.org/0000-0003-1625-7436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 28-year-old male with a relatively short history of progressive dyspnea and a large pericardial effusion with tamponade was found to have an intracardiac mass localized in right atrium (RA) on echocardiography. Multimodality imaging revealed an irregular mass abutting the lateral wall of RA, with infiltration into surrounding pericardium and superior venacava. Positron emission tomography (PET) scan confirmed the mass as metabolically active lesion, along with uptake in mediastinal structures and lymph nodes. After an unrewarding percutaneous endomyocardial biopsy, open surgical biopsy was performed. Histologic examination confirmed the diagnosis of cardiac angiosarcoma. Unfortunately, patient had refractory shock and recurrent massive pericardial effusion (hemorrhagic) after biopsy and succumbed. The case highlights diagnostic dilemma of pericardial effusion in tuberculosis-endemic areas, role of multi-modality imaging in confirming cardiac malignancy and poor outcome of such patients.

Indexed as

AngiosarcomaCardiac imagingCardiac massPericardial effusion

Identifiers

PMID40862098

DOI10.34172/jcvtr.025.33285

PMCPMC12375422

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.