Evidence map›Paper›PMID 40862094›Full record

ArticleChem2025

Design of light- and chemically responsive protein assemblies through host-guest interactions.

Zhiyin Zhang, Huat T Chiang, Ying Xia, Nicole Avakyan, Ravi R Sonani, Fengbin Wang, Edward H Egelman, James J De Yoreo, Lilo D Pozzo, F Akif Tezcan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhiyin ZhangDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Huat T ChiangDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
Ying XiaDepartment of Materials Science and Engineering, University of Washington, Seattle 98195, WA, Physical, USA.
Nicole AvakyanDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.
Ravi R SonaniDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville 22903, VA, USA.
Fengbin WangDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville 22903, VA, USA.
Edward H EgelmanDepartment of Biochemistry and Molecular Genetics, University of Virginia, Charlottesville 22903, VA, USA.
James J De YoreoDepartment of Materials Science and Engineering, University of Washington, Seattle 98195, WA, Physical, USA.
Lilo D PozzoDepartment of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
F Akif TezcanDepartment of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA.

Funding

The Stanford-SLAC CryoEM Center supplementU24GM129541 · NIGMS · STANFORD UNIVERSITY · PI CHIU, WAH, HEDMAN, BRITT · 2018 to 2023
$54.8M
Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic ResolutionR35GM122510 · NIGMS · UNIVERSITY OF VIRGINIA · PI EDWARD H. EGELMAN · 2017 to 2026
$7.3M
JEOL JEM-1400Plus Transmission Electron MicroscopeS10OD023527 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FARQUHAR, MARILYN GIST · 2017 to 2017
$579k
NIGMS NIH HHS R35 GM122510NIGMS NIH HHS U24 GM129541NIH HHS S10 OD023527
6 · The paper itself

Abstract

Host-guest interactions have been widely used to build responsive materials and molecular machines owing to their inherently dynamic nature, interaction specificity, and responsiveness to diverse stimuli. Here we have set out to exploit these advantages of host-guest chemistry in the design of dynamic protein assemblies, using a

Indexed as

barrierless growthchemical responsehost-guest interactionslight responsenanotubular assembliesprotein self-assemblysupramolecular chemistry

Identifiers

PMID40862094
PMCPMC12373406

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.