Evidence map›Paper›PMID 40862018›Full record

ReviewOrthopaedic journal of sports medicine2025

Biomechanical Properties of the All-Inside Anterior Cruciate Ligament Graft: A Scoping Review of Laboratory Evidence on Graft Configuration and Fixation.

Amirzeb Aurangzeb, Sir Young James Loh

Abstract readReview
In one paragraph

Review in Orthopaedic journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Amirzeb AurangzebDepartment of Orthopaedic Surgery, Changi General Hospital, Singapore.ORCID https://orcid.org/0000-0002-3536-9145
Sir Young James LohDepartment of Orthopaedic Surgery, Changi General Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: There are limited comparisons of graft configurations and fixation methods for the all-inside anterior cruciate ligament (ACL) technique based on a laboratory investigation. Purpose/Hypothesis: This review aimed to evaluate the biomechanical data from controlled laboratory studies on different graft configurations and fixation methods in correlation to graft strength and stability in all-inside ACL reconstruction. It was hypothesized that graft configuration and supplementary fixation would significantly contribute to graft strength and stability. Study Design: Scoping review. Methods: A literature search was conducted via PubMed on January 15, 2025, including studies that examined all-inside ACL graft techniques in a controlled biomechanical manner; reported data on stiffness and/or ultimate load to failure, and utilized cadaveric, porcine, or bovine tendons with cyclic loading and pull-to-failure testing protocols. A total of 150 studies were shortlisted before being narrowed down to 11 biomechanical studies, with descriptive statistical analysis performed. Results: This review demonstrated that quadrupled ACL grafts outperformed tripled grafts in stiffness and load to failure. Adjustable-loop devices provided robust primary fixation, while supplementary fixation further enhanced graft stability. Overall, 3 failure modes emerged: graft failure, fixation failure, and suture failure, directly linked to surgical technique choices. Findings established evidence-based benchmarks for optimizing all-inside ACL reconstruction outcomes. Conclusion: Our search and review demonstrated that a quadruple-folded graft with the side-to-side suturing technique, suspended by 2 adjustable-loop devices with additional tensioning and knot tying, and supplementary fixation with tibial reinforcement appears to offer the most stability. This has the potential to optimize functional recovery after ACL reconstruction via improved graft stability and reduced rerupture rates.

Indexed as

ACLall-insidebiomechanicsgraft preparation

Identifiers

PMID40862018
PMCPMC12374034

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.