Evidence map›Paper›PMID 40861997›Full record

ArticleRSC advances2025

Novel self-assembled metal-phenolic nanoplatforms for triple-negative breast cancer treatment: photothermal-chemotherapy/ferroptosis synergy inducing immunogenic cell death.

Bohao Peng, Ruoyao Wang, Tian Li, Xiaoqing Yu, Zhiyu Wang, Xiyang Zhang, Yuanfeng Tan, Long Cheng, Lu Yang

Abstract read
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bohao PengDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 302118@cqmu.edu.cn.
Ruoyao WangDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 302118@cqmu.edu.cn.
Tian LiDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 302118@cqmu.edu.cn.
Xiaoqing YuDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 302118@cqmu.edu.cn.
Zhiyu WangDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 302118@cqmu.edu.cn.
Xiyang ZhangDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 302118@cqmu.edu.cn.
Yuanfeng TanDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 302118@cqmu.edu.cn.
Long ChengUltrasound Department of the Second Affiliated Hospital, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 304188@hospital.cqmu.edu.cn.
Lu YangDepartment of Breast and Thyroid Surgery, The Second Affiliated Hospital of Chongqing Medical University Chongqing 400010 P. R. China 302118@cqmu.edu.cn.ORCID https://orcid.org/0000-0001-7333-8756

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Triple-negative breast cancer (TNBC) poses a serious threat to women's health. Currently, chemotherapy remains the first-line treatment in the clinic, and more comprehensive treatments are urgently needed to improve the therapeutic efficacy of TNBC. Emerging studies have indicated that photothermal therapy, ferroptosis and immunotherapy also play crucial roles in TNBC treatment. Iron based metal-phenolic networks (MPNs), an emerging class of nanomaterials, are attracting great attention in tumor related research due to their unique structural features. These features endow MPNs with outstanding catalytic efficiency for the Fenton reaction and excellent metal-ligand conversion properties, offering promising prospects for photothermal and photodynamic therapies as well as combined treatment strategies for tumors. In this study, a novel iron-based metal-phenolic nanoplatform, namely MTO-loaded TA/Fe nanocomposites (MFTA), was synthesized. Mitoxantrone (MTO), a commonly used anthracycline, was employed along with ferric chloride (FeCl

Identifiers

PMID40861997
PMCPMC12377025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.