Evidence map›Paper›PMID 40861992›Full record

ArticleRSC advances2025

A dual-type I/II NIR photosensitizer for effective cancer photodynamic therapy with enhanced ROS generation.

Shuhua Cao, Yuchang Liu, Xishi Tai, Li Shen, Hekai Yang, Fahui Li, Binglin Sui, Pengju Ma, Lingxuan Zhu, Bin Gao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shuhua CaoCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China.ORCID https://orcid.org/0000-0002-7343-522X
Yuchang LiuCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China.
Xishi TaiCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China.
Li ShenCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China.ORCID https://orcid.org/0000-0002-4781-3637
Hekai YangSchool of Pharmacy, Shandong Second Medical University No. 7166 Baotong Street Weifang 261053 P. R. China.
Fahui LiSchool of Pharmacy, Shandong Second Medical University No. 7166 Baotong Street Weifang 261053 P. R. China.
Binglin SuiCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China.
Pengju MaCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China.
Lingxuan ZhuCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China.
Bin GaoCollege of Chemistry, Chemical and Environmental Engineering, Weifang University No. 5147 Dongfeng Street Weifang 261061 P. R. China.
Anlin WangAffiliated Beijing Chaoyang Hospital, Capital Medical University No. 8 Gongren Tiyuchang Nanlu, Chaoyang District Beijing 100020 P. R. China jordan0309@126.com.
Mohammad AzamDepartment of Chemistry, College of Science, King Saud University PO Box 2455 Riyadh 11451 Saudi Arabia.ORCID https://orcid.org/0000-0002-4274-2796

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Based on the cyanine dye scaffold, two photosensitizers (PSs) (C1 and C2) were successfully synthesized. These PSs exhibited a maximum absorption wavelength of 660 nm, falling within the near-infrared window. Compared to the commercially available photosensitizer ICG, the newly developed PSs demonstrated enhanced reactive oxygen species (ROS) generation under lower light doses. Notably, these PSs can simultaneously produce both singlet oxygen (

Identifiers

PMID40861992
PMCPMC12376870

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.