Evidence map›Paper›PMID 40861894›Full record

ArticleFrontiers in physiology2025

Functional deletion of α7 nicotinic acetylcholine receptor impairs Ca

Beatrice Cannata, Laura Sposito, Martina Albini, Giuseppe Aceto, Giulia Puliatti, Giacomo Lazzarino, Cristian Ripoli, Maria Rosaria Tropea, Daniela Puzzo, Roberto Piacentini and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Beatrice Cannata *Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Laura Sposito *Department of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Martina AlbiniDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Giuseppe AcetoDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Giulia PuliattiDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Giacomo LazzarinoDepartmental Faculty of Medicine, UniCamillus - Saint Camillus International University of Health Sciences, Rome, Italy.
Cristian RipoliDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Maria Rosaria TropeaDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Daniela PuzzoDepartment of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy.
Roberto PiacentiniDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.
Claudio GrassiDepartment of Neuroscience, Università Cattolica del Sacro Cuore, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alpha7 nicotinic acetylcholine receptors (α7-nAChRs) are ionotropic, Ca

Indexed as

acethylcholineAMPAglutamatehippocampusNMDAα7 nAChRs

Identifiers

PMID40861894
PMCPMC12370769

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.