Evidence map›Paper›PMID 40861857›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Analysis of compliance issues and influencing factors in the management of BSL-2 laboratories for pathogenic microorganisms in Lishui, China.

Ying Cong, Jinkai Li, Dingshuo Lou, Jianliang Zhu, Deyong Zhang, Dongqing Cheng, Xiuying Chen

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying Cong *Lishui Center for Disease Control and Prevention, Lishui, China.
Jinkai Li *School of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, China.
Dingshuo LouLishui Center for Disease Control and Prevention, Lishui, China.
Jianliang ZhuLishui Center for Disease Control and Prevention, Lishui, China.
Deyong ZhangLishui Center for Disease Control and Prevention, Lishui, China.
Dongqing ChengSchool of Medical Technology and Information Engineering, Zhejiang Chinese Medical University, Hangzhou, China.
Xiuying ChenLishui Center for Disease Control and Prevention, Lishui, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The management of biosafety laboratories for pathogenic microorganisms is directly related to public health and the effectiveness of biological experiments. However, persistent non-compliance issues in biosafety level 2 (BSL-2) laboratory management remain a challenge. This study aimed to assess the quality control of BSL-2 laboratories for pathogenic microorganisms in Lishui. Methods: By combining the Biosafety Online Supervision Systems and on-site inspections, this study assessed the quality control of 73 medical institutions and the 128 biosafety laboratories under their management in Lishui. Results: The results discovered that the 73 medical institutions had low compliance rates in several fields: Responsibilities of the biosafety management (80.82%), development of system documentation (65.75%), risk assessment (84.56%), training of laboratory personnel (82.19%), and biosafety labeling (52.05%). Additionally, 128 laboratories had low pass rates for the access control management system (85.94%), hand/eye wash and shower stations (85.94%), and biosafety cabinet operations (89.06%). Conclusion: This study demonstrates that future efforts should focus on strengthening laboratory personnel training and implementing biosafety management responsibilities to ensure safe and regulation-compliant operations in laboratories handling pathogenic microorganisms.

Indexed as

biosafetylaboratory managementonline supervision systemspathogenic microorganismsquality control

Identifiers

PMID40861857
PMCPMC12371245

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.