Evidence map›Paper›PMID 40861838›Full record

ArticleIranian journal of medical sciences2025

Impact of Sociodemographic, Clinical, and Genetic Factors and

Gulmira Zhurabekova, Aru Balmagambetova, Zhibek Oralkhan, Maygul Sarsenova, Guliya Toichiyeva, Nazym Altynbay, Azhar Malik, Kuanysh Tastambek, Akzhenis Berdalinova

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Article in Iranian journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Gulmira ZhurabekovaDepartment of Normal and Topographic Anatomy with Operative Surgery, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Aru BalmagambetovaDepartment of Normal and Topographic Anatomy with Operative Surgery, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Zhibek OralkhanDepartment of Fundamental Medicine, Faculty of Medicine and Health Care, Al-Farabi Kazakh National University, Tole bi 96, 050012 Almaty, Kazakhstan.
Maygul SarsenovaDepartment of Normal and Topographic Anatomy with Operative Surgery, West Kazakhstan Marat Ospanov Medical University, Aktobe 030019, Kazakhstan.
Guliya ToichiyevaInternational Clinic of Reproductive Health "PERSONA" LLP, Almaty 050063, Kazakhstan.
Nazym AltynbaySRI "Sustainability of Ecology and Bioresources", Al-Farabi Kazakh National University, Al-Farabi 71, Almaty, 050040, Kazakhstan.
Azhar MalikDepartment of Fundamental Medicine, Faculty of Medicine and Health Care, Al-Farabi Kazakh National University, Tole bi 96, 050012 Almaty, Kazakhstan.
Kuanysh TastambekSRI "Sustainability of Ecology and Bioresources", Al-Farabi Kazakh National University, Al-Farabi 71, Almaty, 050040, Kazakhstan.
Akzhenis BerdalinovaDepartment of Fundamental Medicine, Faculty of Medicine and Health Care, Al-Farabi Kazakh National University, Tole bi 96, 050012 Almaty, Kazakhstan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Premature birth (delivery before 37 weeks of gestation) is a leading cause of neonatal morbidity and mortality worldwide. Specific genetic polymorphisms were associated with immune and inflammatory pathways that might contribute to its pathogenesis. This study investigated the associations between preterm birth and sociodemographic indicators, clinical outcomes, genetic polymorphisms, and microbial factors in Kazakh women. Methods: This case-control study was conducted from September 2022 to September 2023. It enrolled women with preterm and full-term births in Kyzylorda, Kazakhstan. Data included sociodemographic, clinical variables, genotyping ( Results: Sociodemographic analysis showed no significant differences between the studied groups, except for a higher prevalence of previous preterm birth in the case group. Clinical comparisons revealed significantly lower gestational age at delivery, reduced newborn weight and height, decreased placental weight and dimensions, lower hemoglobin levels, and erythrocyte counts in preterm cases. Genetic analysis demonstrated that all women with preterm labor carried the homozygous AA genotype of Conclusion: These findings suggested that a history of preterm birth, specific genetic polymorphisms, and microbial factors collectively were associated with an increased risk of preterm birth.

Indexed as

Fusobacterium InfectionsFusobacterium nucleatumPremature BirthAdultCase-Control StudiesFemaleHumansInfant, NewbornKazakhstanMannose-Binding LectinPregnancyRisk FactorsSociodemographic FactorsToll-Like Receptor 2Mannose-Binding LectinMBL2 protein, humanTLR2 protein, humanToll-Like Receptor 2Clinical studyFusobacterium nucleatumPolymorphism, GeneticPremature birthSociodemographic factors

Identifiers

PMID40861838
PMCPMC12374060

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.