Evidence map›Paper›PMID 40861765›Full record

ArticleCureus2025

A Long-Term (41 Years) Radiographic Follow-Up Study of the Onset and Development of a Jawbone Lesion in a Patient With Gnathodiaphyseal Dysplasia.

Riyu Koguchi, Haruhisa Watanabe, Mai Nishiura, Tadahiro Iimura, Yutaka Maruoka

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Riyu KoguchiDepartment of Oral Diagnosis and Medicine, Hokkaido University, Faculty of Dental Medicine/Graduate School of Dental Medicine, Sapporo, JPN.
Haruhisa WatanabeDepartment of Pharmacology, Hokkaido University, Faculty of Dental Medicine/Graduate School of Dental Medicine, Sapporo, JPN.
Mai NishiuraDepartment of Dentistry for Children and Disabled Persons, Hokkaido University, Faculty of Dental Medicine/Graduate School of Dental Medicine, Sapporo, JPN.
Tadahiro IimuraDepartment of Pharmacology, Hokkaido University, Faculty of Dental Medicine/Graduate School of Dental Medicine, Sapporo, JPN.
Yutaka MaruokaDepartment of Oral Surgery, National Center for Global Health and Medicine, Japan Institute for Health Security, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gnathodiaphyseal dysplasia (GDD) is an autosomal dominant syndrome characterized by bone fragility, sclerosis of tubular bones, and cemento-osseous lesions of the jawbones. This report describes the long-term radiographic follow-up study of jaw lesions in a GDD-affected woman of >40 years of age from the age of one onward. At three years of age, widening of the diaphyseal cortices in the femur and radius was observed, although no symptoms were observed in the jawbones. At nine years of age, we observed a slightly sclerotic appearance in the alveolar and jawbones adjacent to the permanent tooth roots. After completion of the secondary dentition at 14 years of age, increased density of the sclerotic mass was clearly observed. Although the etiology and pathogenesis are uncertain, this study observed that the onset of the jawbone lesion had already appeared after the mixed dentition stage, and the sclerotic mass developed with age.

Indexed as

autosomal dominant genetic disorderbone metabolismcemento-osseous lesiongnathodiaphyseal dysplasia (gdd)jaw bone

Identifiers

PMID40861765
PMCPMC12375413

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.