Evidence map›Paper›PMID 40861735›Full record

ArticleCureus2025

Role of Medication Reconciliation in Managing Bradycardia: A Rare Cause of Medication-Induced Sinus Bradycardia.

Buthainah Alhwarat, Khalid Sawalha, Ibrahim Alshaghdali, Abdelmoniem Moustafa, Hakan Paydak

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Buthainah AlhwaratInternal Medicine, University of Arkansas for Medical Sciences, Little Rock, USA.
Khalid SawalhaCardiovascular Disease, University of Arkansas for Medical Sciences, Little Rock, USA.
Ibrahim AlshaghdaliClinical Cardiac Electrophysiology, University of Arkansas for Medical Sciences, Little Rock, USA.
Abdelmoniem MoustafaClinical Cardiac Electrophysiology, University of Arkansas for Medical Sciences, Little Rock, USA.
Hakan PaydakElectrocardiology and Clinical Cardiac Electrophysiology, University of Arkansas for Medical Sciences, Little Rock, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sinus bradycardia is defined as a heart rate of less than 60 beats per minute (bpm), and it can be attributed to many etiologies, some of which are reversible, including but not limited to acute coronary syndrome, active infections, electrolyte imbalances, hypothyroidism, and medications. We report the case of a 64-year-old man who was admitted to the intensive care unit for the management of status epilepticus, where he developed new-onset, life-threatening sinus bradycardia, requiring placement on support with two inotropic agents (epinephrine and dopamine) due to persistent hemodynamic instability. Cardiology was consulted as a result, and after extensive workup, including review of past medical conditions, laboratory testing, and telemetry review, including that for reversible etiologies, we identified one of the antiepileptic agents on his medication list as the culprit of his sinus bradycardia. This case serves to contribute to existing, very limited, clinical data on its adverse cardiovascular effects.

Indexed as

antiepileptic medicationsarrhythmiaconduction abnormalitylacosamidemedicationsinus bradycardia

Identifiers

PMID40861735
PMCPMC12372550

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.